An integrated encyclopedia of DNA elements in the human genome
An integrated encyclopedia of DNA elements in the human genome is a dataset published in Nature (2012). On theSindex it has a DataRank of 23.8, placing it in the top 2.5% of the data-sharing corpus. It has been cited 19,311 times, with 199 citing works in its 1-hop citation network. Its calibrated FAIR score is 78/100.
Abstract
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied protein-coding regions. Many discovered candidate regulatory elements are physically associated with one another and with expressed genes, providing new insights into the mechanisms of gene regulation. The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide interpretation of this variation. Overall, the project provides new insights into the organization and regulation of our genes and genome, and is an expansive resource of functional annotations for biomedical research.
›Data sources & pipeline
FAIR Checklist
Context only (not used in score)- Has DOI
- Indexed in repositories
- Open Access
- DataCite relations
- Linked datasets
- Dataset classification
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
DataRank Breakdown
Base Score Contribution
1.5
From this paper's citation signal
Citation Network Contribution
22.4
From 199 citing papers with measurable signal
Top 5 citers driving the network score
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
- A global reference for human genetic variationNature201519,823 citationsDataRank 11.1Top 19%
- NCBI GEO: archive for functional genomics data sets—updateNucleic Acids Research201210,702 citationsDataRank 20.2Top 5%
- The Genotype-Tissue Expression (GTEx) projectNature Genetics20139,949 citationsDataRank 18.2Top 8%
- A map of human genome variation from population-scale sequencingNature20108,067 citationsDataRank 32.4Top 1%
- Initial sequencing and comparative analysis of the mouse genomeNature20027,236 citationsDataRank 16.2Top 10%
Why this DataRank?
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 6% comes from its base citations and 94% from the citation network (199 citing papers contributed measurable signal).
- Base score B(p)
- log1p(citation_count) — grows sub-linearly, so a paper with 1,000 citations is not 10× a paper with 100.
- Network N(p)
- Σ over citers of log1p(Cq) ÷ max(outdegreeq, 1). Being cited by a highly-cited paper with few references counts most.
- Damping factor d = 0.85
- DataRank = (1−d)·B(p) + d·N(p) — the two cards above are each already multiplied by their share.
- Self-citations excluded
- Citers sharing any OpenAlex author ID with this paper are filtered out before the network sum.
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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