Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma

Leukemia(2020)10.1038/s41375-020-0962-2Source: DataRank Database

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma is a research paper published in Leukemia (2020). On theSindex it has a DataRank of 0. It has been cited 36 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access36 citations

Download PDF

Cite:

Linked data & code

t(4;14) as a biomarker of Statin sensitivity in Multiple Myeloma · Code Ocean

doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 1.56)OA: hybridTopics (86)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (12)

Petr Smirnov ORCID,Zhihua Li ORCID,Emily Branchard,Jenna E. van Leeuwen ORCID,Jonathan D. Licht ORCID

Live enrichment

PubMed:32665698 PMC:PMC7359767 OpenAlex:https://openalex.org/W3042695800

U.S. Department of Health & Human Services | National Institutes of Health

Grant: CA195732

Terry Fox Research Institute

Grant: 1064

Canadian Cancer Society Research Institute

Grant: 706394

CIHR

Grant: 142263

NCI NIH HHS

Grant: R01 CA195732

National Institutes of Health

Grant: 5R01CA195732-04

The Role of MMSET in the Pathogenesis and Progression of Lymphoid Malignancy

Canadian Institutes of Health Research

Grant: unidentified

unidentified

Leukemia and Lymphoma Society

FWCI

1.56

Citation Percentile

0.8%

Influential Citations

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.nature.com/articles/s41375-020-0962-2.pdf

HYBRIDhttps://www.nature.com/articles/s41375-020-0962-2.pdf

publisherhttps://www.nature.com/articles/s41375-020-0962-2.pdf

publisherhttp://www.nature.com/articles/s41375-020-0962-2.pdf

publisherhttp://www.nature.com/articles/s41375-020-0962-2

Fields of Study

Cancer, Lipids, and MetabolismUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and DiseaseMedicine0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorBortezomibCell ProliferationChromosomes, Human, Pair 14Chromosomes, Human, Pair 4FemaleFluvastatinGene Expression Regulation, NeoplasticHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMevalonic AcidMiceMice, Inbred NODMice, SCIDMultiple MyelomaPolyisoprenyl PhosphatesTranslocation, GeneticTumor Cells, CulturedXenograft Model Antitumor Assays

MeSH Terms

BortezomibFluvastatinAnimalsAntineoplastic AgentsChromosomes, Human, Pair 14Chromosomes, Human, Pair 4FemaleHumansMevalonic AcidMultiple MyelomaPolyisoprenyl PhosphatesTranslocation, GeneticTumor Cells, CulturedBiomarkers, TumorGene Expression Regulation, NeoplasticMice, SCIDMice, Inbred NODApoptosisHydroxymethylglutaryl-CoA Reductase InhibitorsXenograft Model Antitumor AssaysCell ProliferationMice

Keywords

Mevalonate pathwayGeranylgeranylationBortezomibGeranylgeranyl pyrophosphateStatinCancer researchApoptosisMevalonic acidProteasome inhibitorBiologyMultiple myelomaCarfilzomibMedicinePharmacologyPrenylationInternal medicineImmunologyBiochemistryAntineoplastic AgentsMice, SCIDArticleTranslocation, GeneticMicePolyisoprenyl PhosphatesMice, Inbred NODBiomarkers, TumorAnimalsHumansFluvastatinCell ProliferationChromosomes, Human, Pair 14Gene Expression Regulation, NeoplasticFemaleChromosomes, Human, Pair 4Hydroxymethylglutaryl-CoA Reductase Inhibitors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 10: 10. No inequalitySDG 0: Good health and well-being

t(4;14) as a biomarker of Statin sensitivity in Multiple Myeloma

10.24433/co.7372187.v1Code Ocean

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma

FAIR Checklist

Authors (12)

Funding (8 grants)

Impact

Open Access

Topics

Linked Datasets (1)

Annotations (Europe PMC)