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Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress

Molecular Psychiatry(2022)10.1038/s41380-021-01398-2Source: DataRank Database

Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress is a research paper published in Molecular Psychiatry (2022). On theSindex it has a DataRank of 0.596. It has been cited 52 times.

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0.596DataRank · unranked

Scored on demand from live citation data

Open Access52 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 3.70)OA: bronzeTopics (67)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.596

From this paper's citation signal

Citation Network Contribution

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Authors (19)

Adam X. Maihofer ORCID,Agaz H. Wani ORCID,John R. Pfeiffer ORCID,Elizabeth Ketema ORCID,Andrew Ratanatharathorn ORCID

Live enrichment

PubMed:34992238 PMC:PMC9106882 OpenAlex:https://openalex.org/W4205764280

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Grant: 2R01MH108826

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Grant: 2R01MH106595

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Grant: U01MH087981

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: 917.18.336

NIMH NIH HHS

Grant: R01 MH106595

NIMH NIH HHS

Grant: R01 MH124847

NIMH NIH HHS

Grant: R01 MH108826

National Institutes of Health

Grant: 5R01MH106595-02

Psychiatric Genomics Consortium for PTSD

National Institutes of Health

Grant: 5U01MH087981-04

Modifiable Risk and Protective Factors for Suicidal Behaviors in the US Army

National Institutes of Health

Grant: 5R01MH108826-07

The Impact of Traumatic Stress on the Methylome: implications for PTSD

The Marine Corps, Navy Bureau of Medicine and Surgery

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Health Services Research and Development

Dutch Ministry of Defence

FWCI

3.70

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: Springer Nature TDM

journalhttps://www.nature.com/articles/s41380-021-01398-2.pdf

publisherhttps://www.nature.com/articles/s41380-021-01398-2.pdf

publisherhttps://www.nature.com/articles/s41380-021-01398-2

journalhttps://doi.org/10.1038/s41380-021-01398-2

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34992238

Fields of Study

Epigenetics and DNA MethylationPosttraumatic Stress Disorder ResearchTryptophan and brain disorders0301 basic medicine03 medical and health sciencesAdaptor Proteins, Signal TransducingDNA MethylationEpigenesis, GeneticEpigenomeHumansImmune SystemMaleMilitary PersonnelOxidative StressStress Disorders, Post-Traumatic

MeSH Terms

EpigenomeHumansImmune SystemMaleMilitary PersonnelStress Disorders, Post-TraumaticOxidative StressDNA MethylationEpigenesis, GeneticAdaptor Proteins, Signal Transducing

Keywords

dNaMEpigeneticsDNA methylationGeneMethylationImmune systemBiomarkerOxidative stressEXPRESSIONDISORDERMaleTRANSMISSIONPROTEINMedical and Health SciencesArticleEpigenesis, GeneticTHROMBOXANE RECEPTORACTIVATIONPATHWAYStress Disorders, Post-TraumaticEpigenomeGeneticGenetics2.1 Biological and endogenous factorsHumansAetiologyStress DisordersPROSTANOID RECEPTORSAdaptor Proteins, Signal TransducingPsychiatryHuman GenomePsychology and Cognitive SciencesSignal TransducingAdaptor ProteinsBiological SciencesPost-Traumatic Stress Disorder (PTSD)Mental HealthGood Health and Well BeingMilitary PersonnelPost-TraumaticEpigenesisPACKAGE

Sustainable Development Goals

SDG 3: 3. Good health