Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset

Nature Communications(2024)10.1038/s41467-024-45097-2Source: DataRank Database

Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset is a research paper published in Nature Communications (2024). On theSindex it has a DataRank of 0.546. It has been cited 20 times, with 18 citing works in its 1-hop citation network.

N/A

0.546DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access20 citations · 18 citing works in its network

Download PDF

Cite:

Linked data & code

gen hpa uniprot doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE223153 GSE222990 GSE172380 GSE141017

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 3.51)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 84%Citation Network 16%

Base Score Contribution

0.457

From this paper's citation signal

Citation Network Contribution

0.0894

From 7 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 18 citers.

Mesoporous Magnetic Graphene for Serum Metabolic Profiling in Non-Invasive Early Detection and Diagnosis of Pancreatic Ductal Adenocarcinoma
ACS Applied Materials & Interfaces20253 citations57 referencesContributes 0.024
Small molecules enhance the high-efficiency generation of pancreatic ductal organoids
Acta Biochimica et Biophysica Sinica20243 citations61 referencesContributes 0.023
Emerging strategies to investigate the biology of early cancer
Nature reviews. Cancer202456 citations211 referencesContributes 0.019
Organoids in the research of pancreatic neoplasms: cultivation, applications, and limitations
Cancer Letters20253 citations129 referencesContributes 0.011
Pathophysiology-Driven Approaches for Overcoming Nanomedicine Resistance in Pancreatic Cancer
Molecular Pharmaceutics202413 citations250 referencesContributes 0.011

Authors (19)

Michael H. Nipper,A. Domínguez ORCID,Zhenqing Ye ORCID,Naoki Akanuma ORCID,Kevin Lopez ORCID

Live enrichment

PubMed:38280869 PMC:PMC10821902 OpenAlex:https://openalex.org/W4391276528

Cancer Prevention and Research Institute of Texas

Grant: R1219

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R21 CA218968

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK110361

NCI NIH HHS

Grant: P01 CA117969

NCI NIH HHS

Grant: R01 CA237159

NIGMS NIH HHS

Grant: T32 GM148752

NCI NIH HHS

Grant: P30 CA054174

NCI NIH HHS

Grant: R21 CA245437

NIH HHS

Grant: S10 OD030311

NIH HHS

Grant: S10 OD030432

NCI NIH HHS

Grant: R01 CA195651

National Institutes of Health

Grant: 1S10OD030432-01A1

FACSAria Fusion cell sorter for Flow Cytometry Shared Resource

National Institutes of Health

Grant: 5T32GM148752-02

IMSD at UT Health San Antonio

National Institutes of Health

Grant: 5P30CA054174-16

SAN ANTONIO CANCER INSTITUTE

National Institutes of Health

Grant: 5R21CA218968-02

Novel model to study PDAC using normal human pancreatic tissue

National Institutes of Health

Grant: 5R01CA237159-06

Mechanisms of pancreatic cancer initiation and progression from normal human pancreatic tissue

National Institutes of Health

Grant: 1S10OD030311-01

Illumina NovaSeq 6000 Sequencing System

National Institutes of Health

Grant: 5R01DK110361-05

The Hippo signaling pathway in pancreatic epithelial cells orchestrate the inflammatory response R01

William and Ella Owens Medical Research Foundation

FWCI

3.51

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.nature.com/articles/s41467-024-45097-2.pdf

publisherhttps://www.nature.com/articles/s41467-024-45097-2.pdf

publisherhttps://www.nature.com/articles/s41467-024-45097-2

journalhttps://doi.org/10.1038/s41467-024-45097-2

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38280869

Fields of Study

Pancreatic and Hepatic Oncology ResearchRNA modifications and cancerEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsHumansTranscriptomePancreatic NeoplasmsCarcinoma, Pancreatic DuctalCarcinogenesisAcinar CellsGene Expression ProfilingProto-Oncogene Proteins p21(ras)

MeSH Terms

AnimalsHumansPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)Gene Expression ProfilingCarcinoma, Pancreatic DuctalTranscriptomeAcinar CellsCarcinogenesis

Keywords

TranscriptomePrimary (astronomy)BiologyCancer researchComputational biologyGeneticsGeneGene expressionMedical SciencesBioinformaticsCarcinogenesisDigestive System DiseasesScience610DiseasesAcinar CellsArticleBiomedical InformaticsProto-Oncogene Proteins p21(ras)NeoplasmsMedical SpecialtiesMedicine and Health SciencesAnimalsHumansCancer modelsGene Expression ProfilingCarcinomaQGastroenterologyPancreatic NeoplasmsOncologyPancreatic Ductalancreatic cancerCarcinoma, Pancreatic Ductal

Sustainable Development Goals

SDG 0: Good health and well-being