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Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation

Nature Communications(2024)10.1038/s41467-024-45489-4Source: DataRank Database

Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation is a research paper published in Nature Communications (2024). On theSindex it has a DataRank of 0.837. It has been cited 34 times, with 31 citing works in its 1-hop citation network.

N/A

0.837DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access34 citations · 31 citing works in its network

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Linked data & code

bioproject gen doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

SRAPRJNA699369
GEOGSE226556

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 9.64)OA: goldTopics (71)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 64%Citation Network 36%

Base Score Contribution

0.533

From this paper's citation signal

Citation Network Contribution

0.304

From 18 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 31 citers.

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Journal of Nanobiotechnology202433 citations54 referencesContributes 0.065
LKB1 inactivation unleashes prostate cancer lineage plasticity
Cell Research20251 citations12 referencesContributes 0.058
Androgen blockage impairs proliferation and function of Sertoli cells via Wee1 and Lfng
Cell Communication and Signaling20243 citations39 referencesContributes 0.036
Therapeutic targeting of exportin-1 beyond nuclear export
Trends in Pharmacological Sciences202413 citations81 referencesContributes 0.033
Combination of porous Se@SiO2 nanospheres and docetaxel exhibits anti-castration-resistant prostate cancer activity by downregulating ATG14-dependent autophagy
Nano Today20242 citations41 referencesContributes 0.027

Authors (16)

Alyssa J. Buckley,Donghoon Lee ORCID,Alex Hiroto ORCID,Christian H. Nenninger ORCID,Adam W. Olson ORCID

Live enrichment

PubMed:38336745 PMC:PMC10858246 OpenAlex:https://openalex.org/W4391682254

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA070297

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA166894

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA233664

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK104941

NCI NIH HHS

Grant: R01 CA288392

National Institutes of Health

Grant: 7R01CA166894-04

A New Mechanism for Castration Resistant Prostate Cancer

National Institutes of Health

Grant: 2R01CA070297-15A1

Androgen Signaling in prostate cancer progression and CRPC development

National Institutes of Health

Grant: 2R01DK104941-05

Androgen Signaling in Prostatic Sonic Hedgehog Responsive Cells

National Institutes of Health

Grant: 5R01CA233664-05

DNA repair gene mutations and prostate cancer

FWCI

9.64

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.nature.com/articles/s41467-024-45489-4.pdf

publisherhttps://www.nature.com/articles/s41467-024-45489-4.pdf

publisherhttps://www.nature.com/articles/s41467-024-45489-4

journalhttps://doi.org/10.1038/s41467-024-45489-4

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38336745

Fields of Study

Prostate Cancer Treatment and ResearchEstrogen and related hormone effectsCancer, Lipids, and Metabolism0301 basic medicine0303 health sciences03 medical and health sciencesMaleHumansMiceAnimalsAndrogensProstatic Neoplasms, Castration-ResistantAndrogen Antagonistsbeta CateninActive Transport, Cell NucleusWnt Signaling PathwayRibosomal ProteinsReceptors, AndrogenCell Line, TumorHepatocyte Growth Factor

MeSH Terms

Androgen AntagonistsAndrogensAnimalsHumansMaleReceptors, AndrogenRibosomal ProteinsHepatocyte Growth FactorActive Transport, Cell NucleusCell Line, Tumorbeta CateninMiceWnt Signaling PathwayProstatic Neoplasms, Castration-Resistant

Keywords

EnzalutamideProstate cancerWnt signaling pathwayCancer researchAndrogen deprivation therapyAndrogen receptorBiologyAndrogenRibosome biogenesisTMPRSS2CancerSignal transductionMedicineCell biologyInternal medicineEndocrinologyRibosomeRNAGeneticsGeneHormoneMaleRibosomal ProteinsHepatocyte Growth FactorScienceQActive Transport, Cell NucleusAndrogen AntagonistsArticleMiceProstatic Neoplasms, Castration-ResistantReceptors, AndrogenCell Line, TumorAndrogensHumansAnimalsbeta Catenin

Sustainable Development Goals

SDG 3: 3. Good health