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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

Nature(2021)10.1038/s41586-021-03341-5Source: DataRank Database

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis is a research paper published in Nature (2021). On theSindex it has a DataRank of 0.923. It has been cited 469 times.

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0.923DataRank · unranked

Scored on demand from live citation data

Open Access469 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (33 grants)Impact (FWCI 24.54)OA: bronzeTopics (64)Linked Datasets (12)DataCite Reuse (12)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.923

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Citation Network Contribution

Citation network not refreshed for this result

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Authors (26)

Chenyi Xue ORCID,Mustafa Yalçınkaya ORCID,Brian Hardaway ORCID,Sandra Abramowicz,Tong Xiao ORCID

Live enrichment

PubMed:33731931 PMC:PMC8038646 OpenAlex:https://openalex.org/W3139367533

NCI NIH HHS

Grant: R01 CA225231

NIH HHS

Grant: S10 OD020056

NHLBI NIH HHS

Grant: R01 HL137219

NHLBI NIH HHS

Grant: K99 HL157649

NCI NIH HHS

Grant: P01 CA108671

NCI NIH HHS

Grant: P30 CA013696

NHLBI NIH HHS

Grant: R01 HL080472

NHLBI NIH HHS

Grant: R01 HL118567

NIDDK NIH HHS

Grant: T32 DK007647

NHLBI NIH HHS

Grant: F32 HL151051

NHLBI NIH HHS

Grant: F30 HL137327

NCI NIH HHS

Grant: P30 CA008748

NHLBI NIH HHS

Grant: R01 HL134892

NHLBI NIH HHS

Grant: R01 HL148071

NCRR NIH HHS

Grant: S10 RR027050

NCATS NIH HHS

Grant: TL1 TR001875

NHLBI NIH HHS

Grant: R01 HL155431

NHLBI NIH HHS

Grant: R01 HL137663

National Institutes of Health

Grant: 1R01HL137663-01

Mechanisms linking LNK genetic variation to atherothrombosis

National Institutes of Health

Grant: 1F32HL151051-01

Cardiovascular consequences of increased inflammasome activation in Jak2vf-mediated clonal hematopoiesis

National Institutes of Health

Grant: 5TL1TR001875-02

NRSA Training Core

National Institutes of Health

Grant: 5R01HL155431-04

Clonal hematopoiesis, inflammasomes and atherosclerosis

National Institutes of Health

Grant: 1R01CA225231-01

Identification of therapeutic targets for leukemia stem cells in AML-iPSC models

National Institutes of Health

Grant: 3P30CA013696-21S1

CANCER CENTER CORE SUPPORT GRANT

National Institutes of Health

Grant: 5R01HL134892-04

Novel mechanisms of the thrombotic complications of atherosclerosis

National Institutes of Health

Grant: 1F30HL137327-01A1

Transcriptional Regulation of Macrophage Function by LXR in Atherosclerosis

National Institutes of Health

Grant: 5R01HL118567-05

HDL, platelet progenitors, atherosclerosis and thrombosis

National Institutes of Health

Grant: 5P01CA108671-12

MPN Research Consortium

National Institutes of Health

Grant: 5R01HL148071-02

JAK2V617F, clonal hematopoiesis and atherosclerosis

National Institutes of Health

Grant: 1S10RR027050-01A1

Becton Dickinson LSR II Analytical Flow Cytometer

National Institutes of Health

Grant: 5R01HL080472-02

Determinants of Arterial Remodeling in Atherogenesis

National Institutes of Health

Grant: 5R01HL137219-02

Dissecting splicing factor mutations in iPSCs

National Institutes of Health

Grant: 1S10OD020056-01

BD Biosciences Influx

FWCI

24.54

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Springer Nature TDM

journalhttps://www.nature.com/articles/s41586-021-03341-5.pdf

publisherhttps://www.nature.com/articles/s41586-021-03341-5.pdf

publisherhttps://www.nature.com/articles/s41586-021-03341-5

journalhttps://doi.org/10.1038/s41586-021-03341-5

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33731931

Fields of Study

Inflammasome and immune disordersIL-33, ST2, and ILC PathwaysAdipokines, Inflammation, and Metabolic Diseases0301 basic medicine03 medical and health sciences

MeSH Terms

PyroptosisRNA-SeqClonal HematopoiesisGasderminsAnimalsAntibodiesBone MarrowDisease Models, AnimalDNA-Binding ProteinsFemaleHumansInflammationMacrophagesMice, Inbred C57BLCaspase 1Phosphate-Binding ProteinsIntracellular Signaling Peptides and ProteinsAtherosclerosisMiceCaspases, InitiatorInterleukin-1betaInterleukin 1 Receptor Antagonist ProteinJanus Kinase 2InflammasomesSingle-Cell Analysis

Keywords

HaematopoiesisInflammasomeBiologyAIM2PyroptosisInflammationSomatic cellMyeloidImmunologyMacrophageCancer researchCell biologyStem cellGeneticsGeneInflammasomesMacrophagesCaspase 1Interleukin-1betaIntracellular Signaling Peptides and ProteinsJanus Kinase 2AtherosclerosisAntibodiesCaspases, InitiatorDNA-Binding ProteinsMice, Inbred C57BLDisease Models, AnimalInterleukin 1 Receptor Antagonist ProteinMiceBone MarrowAnimalsHumansFemaleClonal Hematopoiesis

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases

10.6084/m9.figshare.25996839.v1figshare

Additional file 1 of Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases

10.6084/m9.figshare.25996839figshare

Additional file 2 of Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases

10.6084/m9.figshare.25997046.v1figshare

Additional file 2 of Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases

10.6084/m9.figshare.25997046figshare

Additional file 1 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660335.v1figshare

Additional file 1 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660335figshare

Additional file 2 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660338.v1figshare

Additional file 2 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660338figshare

Additional file 3 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660341.v1figshare

Additional file 3 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660341figshare

Additional file 4 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660347.v1figshare

Additional file 4 of Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic frontiers

10.6084/m9.figshare.26660347figshare