Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Stepwise activation of a metabotropic glutamate receptor

Nature(2024)10.1038/s41586-024-07327-xSource: DataRank Database

Stepwise activation of a metabotropic glutamate receptor is a research paper published in Nature (2024). On theSindex it has a DataRank of 1.1. It has been cited 41 times, with 39 citing works in its 1-hop citation network.

N/A

1.1DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access41 citations · 39 citing works in its network

Download PDF

Cite:

Data availability

Repositories this paper deposited data in (declared in PubMed).

Protein8T7H, 8T8M, 8TAO, 8T6J

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 7.72)OA: greenTopics (57)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 49%Citation Network 51%

Base Score Contribution

0.561

From this paper's citation signal

Citation Network Contribution

0.580

From 25 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 39 citers.

Efficient screening and discovery of umami peptides in Douchi enhanced by molecular dynamics simulations
Food Chemistry X202415 citations45 referencesContributes 0.062
Apo‐state structure of the metabotropic glutamate receptor 5 transmembrane domain obtained using a photoswitchable ligand
Protein Science20255 citations32 referencesContributes 0.056
Triple Labeling Resolves a GPCR Intermediate State by Using Three-Color Single Molecule FRET
Journal of the American Chemical Society202510 citations43 referencesContributes 0.056
Molecular basis of β-arrestin coupling to the metabotropic glutamate receptor mGlu3
Nature Chemical Biology202516 citations52 referencesContributes 0.054
Delineating the stepwise millisecond allosteric activation mechanism of the class C GPCR dimer mGlu5
Nature Communications202436 citations88 referencesContributes 0.041

Authors (12)

Haoqing Wang ORCID,Chris Habrian,Naomi R. Latorraca ORCID,Jun Xu ORCID,Evan S. O’Brien ORCID

Live enrichment

PubMed:38632403 OpenAlex:https://openalex.org/W4394892337

National Institutes of Health

Grant: 5R01NS119826-03

Conformational mechanisms of mGluR gating and regulation

National Institutes of Health

Grant: 5K99GM148823-02

Decoding Structural Determinants of Efficacy and Specificity in a GPCR Subfamily

National Institutes of Health

Grant: 5R01NS122394-04

Structural Basis of Signal Instigation Through Family C GPCRs

National Institutes of Health

Grant: 5R01NS028471-13

THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION

NIGMS NIH HHS

Grant: K99 GM148823

NINDS NIH HHS

Grant: R01 NS119826

NINDS NIH HHS

Grant: R01 NS122394

NINDS NIH HHS

Grant: R35 NS137408

FWCI

7.72

Citation Percentile

1.0%

Influential Citations

Citation Trend

2024

2025

2026

greenLicense: Springer Nature TDM

repositoryhttps://escholarship.org/content/qt3d38q1j9/qt3d38q1j9.pdf

publisherhttps://www.nature.com/articles/s41586-024-07327-x.pdf

publisherhttps://www.nature.com/articles/s41586-024-07327-x

repositoryhttps://escholarship.org/uc/item/3d38q1j9

Fields of Study

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and SignalingPhotoreceptor and optogenetics researchMedicineChemistry0301 basic medicine03 medical and health sciencesHumansAllosteric RegulationFluorescenceLigandsModels, MolecularProtein BindingProtein DomainsReceptor, Metabotropic Glutamate 5Single Molecule ImagingHeterotrimeric GTP-Binding Proteins

MeSH Terms

Protein DomainsSingle Molecule ImagingAllosteric RegulationFluorescenceHumansLigandsModels, MolecularProtein BindingReceptors, Metabotropic GlutamateHeterotrimeric GTP-Binding ProteinsReceptor, Metabotropic Glutamate 5

Keywords

Metabotropic glutamate receptor 5Metabotropic glutamate receptor 4Metabotropic glutamate receptorMetabotropic glutamate receptor 7Metabotropic glutamate receptor 2Metabotropic glutamate receptor 3Metabotropic glutamate receptor 6Metabotropic receptorGlutamate receptorMetabotropic glutamate receptor 1ChemistryMetabotropic glutamate receptor 8NeuroscienceReceptorBiologyBiochemistryModels, MolecularReceptor, Metabotropic Glutamate 5MolecularLigandsMetabotropic Glutamate 5Heterotrimeric GTP-Binding ProteinsFluorescenceSingle Molecule ImagingAllosteric RegulationProtein DomainsModelsHumansProtein Binding