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Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia

Nature Genetics(2021)10.1038/s41588-021-00829-8Source: DataRank Database

Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia is a research paper published in Nature Genetics (2021). On theSindex it has a DataRank of 0. It has been cited 113 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access113 citations

Cite:

Linked data & code

geo gen

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)Impact (FWCI 15.35)OA: greenTopics (71)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Yuxuan Liu ORCID,Yuannyu Zhang ORCID,Hui Cao ORCID,Junhua Lyu ORCID,Xun Wang ORCID

Live enrichment

PubMed:33833453 PMC:PMC8270111 OpenAlex:https://openalex.org/W3144073050

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: T32CA124334

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA222579

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA230631

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK111430

Cancer Prevention and Research Institute of Texas

Grant: RP160157

Cancer Prevention and Research Institute of Texas

Grant: RP170086

Cancer Prevention and Research Institute of Texas

Grant: RR140025

Cancer Prevention and Research Institute of Texas

Grant: RP180504

Cancer Prevention and Research Institute of Texas

Grant: RP180826

Cancer Prevention and Research Institute of Texas

Grant: RP190417

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Grant: R01GM115682

NIGMS NIH HHS

Grant: R15 GM131263

NCI NIH HHS

Grant: R01 CA248736

NIH HHS

Grant: R21 OD017965

National Institutes of Health

Grant: 1R01CA248736-01

ITIM-receptors for cancer treatment

National Institutes of Health

Grant: 5R01GM115682-08

Suppression of mobile elements by p53 genes

National Institutes of Health

Grant: 1R15GM131263-01

Developmental timing of LINE-1 retrotransposition in mouse models

National Institutes of Health

Grant: 1R21OD017965-01A1

Novel Transgenic Mouse Models for L1 Retrotransposons in Development and Disease

National Institutes of Health

Grant: 5R01CA222579-05

Tumor suppression, p53 and retrotransposons

National Institutes of Health

Grant: 5R01DK111430-03

Molecular Analysis of Transcriptional Enhancers in Hematopoiesis

National Institutes of Health

Grant: 5R01CA230631-05

Targeting Metabolic Liabilities of Leukemia-Initiating Cells

National Institutes of Health

Grant: 5T32CA124334-04

Cancer Biology Training Grant

FWCI

15.35

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Springer TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8270111

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8270111

publisherhttps://www.nature.com/articles/s41588-021-00829-8.pdf

publisherhttps://www.nature.com/articles/s41588-021-00829-8

journalhttps://doi.org/10.1038/s41588-021-00829-8

Fields of Study

Chromosomal and Genetic VariationsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques0303 health sciences03 medical and health sciencesAnimalsCRISPR-Cas SystemsCarcinogenesisCell Line, TumorEpigenesis, GeneticGene Expression Regulation, LeukemicGene SilencingGenome, HumanGenomic InstabilityHematopoiesisHumansLeukemia, MyeloidLong Interspersed Nucleotide ElementsMice, Inbred C57BLMice, KnockoutPhosphoproteinsMice

MeSH Terms

AnimalsHematopoiesisHumansLeukemia, MyeloidMice, Inbred C57BLPhosphoproteinsGenome, HumanGene Expression Regulation, LeukemicMice, KnockoutLong Interspersed Nucleotide ElementsGene SilencingGenomic InstabilityEpigenesis, GeneticCell Line, TumorMiceCarcinogenesisCRISPR-Cas Systems

Keywords

RetrotransposonBiologyGene silencingMyeloid leukemiaEpigeneticsEctopic expressionTransposable elementGeneticsDNA methylationLong terminal repeatPhenotypeMyeloidCancer researchGenomeGeneGene expressionMice, KnockoutCarcinogenesisGene Expression Regulation, LeukemicGenome, HumanPhosphoproteinsGenomic InstabilityEpigenesis, GeneticHematopoiesisMice, Inbred C57BLMiceLong Interspersed Nucleotide ElementsLeukemia, MyeloidCell Line, TumorAnimalsHumansCRISPR-Cas Systems

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being