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Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A–menin to bivalent promoters

Nature Genetics(2025)10.1038/s41588-024-02015-ySource: DataRank Database

Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A–menin to bivalent promoters is a research paper published in Nature Genetics (2025). On theSindex it has a DataRank of 0.434. It has been cited 17 times.

N/A

0.434DataRank · unranked

Scored on demand from live citation data

Open Access17 citations

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 6.66)OA: hybridTopics (42)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.434

From this paper's citation signal

Citation Network Contribution

0

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (30)

Mohini R. Pachai ORCID,Dan Li ORCID,Cindy J. Lee ORCID,Sarah Warda ORCID,Makhzuna N. Khudoynazarova

Live enrichment

PubMed:39806204 OpenAlex:https://openalex.org/W4406334196

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: P50CA092629

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA193837

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: U01CA224044

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA208100

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: P50CA221745

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: P01CA221757

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA233899

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: R01CA228216

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: DP2CA174499

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Grant: P50CA217694

U.S. Department of Defense

Grant: W81XWH-15-1-0124

NCI NIH HHS

Grant: U01 CA252048

NCI NIH HHS

Grant: P30 CA008748

NCI NIH HHS

Grant: U54 CA224079

NCI NIH HHS

Grant: R01 CA265026

NCI NIH HHS

Grant: R01 CA280657

FWCI

6.66

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://www.nature.com/articles/s41588-024-02015-y.pdf

publisherhttps://www.nature.com/articles/s41588-024-02015-y.pdf

publisherhttps://www.nature.com/articles/s41588-024-02015-y

journalhttps://doi.org/10.1038/s41588-024-02015-y

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39806204

Fields of Study

Epigenetics and DNA MethylationRenal and related cancersBladder and Urothelial Cancer TreatmentsAnimalsUrotheliumMicePromoter Regions, GeneticCarcinogenesisHumansMice, KnockoutDNA-Binding ProteinsHistone-Lysine N-MethyltransferaseMyeloid-Lymphoid Leukemia ProteinCell Transformation, NeoplasticUrinary Bladder NeoplasmsNeoplasm ProteinsGene Expression Regulation, Neoplastic

MeSH Terms

AnimalsUrinary Bladder NeoplasmsCell DifferentiationCell Transformation, NeoplasticDNA-Binding ProteinsHumansNeoplasm ProteinsPromoter Regions, GeneticHistone-Lysine N-MethyltransferaseGene Expression Regulation, NeoplasticMice, KnockoutUrotheliumMiceMyeloid-Lymphoid Leukemia ProteinCarcinogenesisErbB Receptors

Keywords

BiologyCarcinogenesisUrotheliumBivalent (engine)PromoterGeneticsCancer researchGeneAnatomy

Sustainable Development Goals

SDG 0: No poverty