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Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

Nature Immunology(2020)10.1038/s41590-020-0654-0Source: DataRank Database

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation is a research paper published in Nature Immunology (2020). On theSindex it has a DataRank of 0.798. It has been cited 204 times.

N/A

0.798DataRank · unranked

Scored on demand from live citation data

Open Access204 citations

Cite:

Linked data & code

geo uniprot

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (35 grants)Impact (FWCI 10.53)OA: greenTopics (139)Linked Datasets (6)DataCite Reuse (6)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.798

From this paper's citation signal

Citation Network Contribution

0

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (30)

Jae Kyu Ryu ORCID,Sophia Bardehle,Anke Meyer‐Franke,Kenny Kean‐Hooi Ang,Chris Wilson

Live enrichment

PubMed:32284594 PMC:PMC7523413 OpenAlex:https://openalex.org/W3016013187

U.S. Department of Health & Human Services | National Institutes of Health

Grant: NS097976

U.S. Department of Health & Human Services | National Institutes of Health

Grant: AG064926

U.S. Department of Health & Human Services | National Institutes of Health

Grant: AI007334

U.S. Department of Health & Human Services | National Institutes of Health

Grant: NS110973

U.S. Department of Health & Human Services | National Institutes of Health

Grant: NS096920

U.S. Department of Health & Human Services | National Institutes of Health

Grant: GM115622

U.S. Department of Health & Human Services | National Institutes of Health

Grant: AI131624

U.S. Department of Health & Human Services | National Institutes of Health

Grant: NS092835

U.S. Department of Health & Human Services | National Institutes of Health

Grant: NS108159

Conrad N. Hilton Foundation

Grant: 17348

National Multiple Sclerosis Society

Grant: FastForward

National Multiple Sclerosis Society

Grant: FG 1944-A-1

National Multiple Sclerosis Society

Grant: FG-1708-28925

National Multiple Sclerosis Society

Grant: FG-1507-05496

American Heart Association

Grant: 16SDG30170014

NIAID NIH HHS

Grant: T32 AI007334

NIAID NIH HHS

Grant: R01 AI131624

NINDS NIH HHS

Grant: R21 NS108159

NINDS NIH HHS

Grant: F32 NS096920

NINDS NIH HHS

Grant: R01 NS092835

NIGMS NIH HHS

Grant: R01 GM115622

NIA NIH HHS

Grant: RF1 AG064926

NIAID NIH HHS

Grant: P30 AI027763

NINDS NIH HHS

Grant: R35 NS097976

NIGMS NIH HHS

Grant: P41 GM103504

National Institutes of Health

Grant: 5R01NS092835-02

Disease relevance of CD20 expression on T cells in multiple sclerosis patients

National Institutes of Health

Grant: 5R01GM115622-05

REAL-TIME QUANTITATIVE IMAGING OF INTRACELLULAR BIOTHIOL DYNAMICS

National Institutes of Health

Grant: 5R21NS108159-02

Influence of NMO gut microbiota on CNS autoantigen-specific T cell responses

National Institutes of Health

Grant: 5F32NS096920-02

Role of Fibrinogen in Neuronal Dysfunction

National Institutes of Health

Grant: 5R01AI131624-05

Repertoire selection of AQP4-specific T cells that cause CNS autoimmunedisease

National Institutes of Health

Grant: 1RF1AG064926-01

Fibrinogen and vascular cognitive impairment: mechanisms, imaging, therapeutics

National Institutes of Health

Grant: 5K02NS110973-03

Fibrinogen-mediated mechanisms of preterm infant brain injury

National Institutes of Health

Grant: 5R35NS097976-04

Neurovascular Interactions: Mechanisms, imaging, therapeutic potential

National Institutes of Health

Grant: 2P41GM103504-06

Core_Training

National Institutes of Health

Grant: 5T32AI007334-02

MOLECULAR AND CELLULAR IMMUNOLOGY

FWCI

10.53

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Springer TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7523413

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7523413

publisherhttp://www.nature.com/articles/s41590-020-0654-0.pdf

publisherhttp://www.nature.com/articles/s41590-020-0654-0

journalhttps://doi.org/10.1038/s41590-020-0654-0

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersImmune cells in cancer0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsAntioxidantsDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleGene Expression ProfilingGene Regulatory NetworksHigh-Throughput Screening AssaysHumansImmunity, InnateIsoxazolesMiceMice, Inbred C57BLMice, Mutant StrainsMicrogliaMultiple SclerosisNeurogenic InflammationOxidative StressSequence Analysis, RNASingle-Cell Analysis

MeSH Terms

AnimalsAntioxidantsDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleHumansImmunity, InnateIsoxazolesMice, Inbred C57BLMice, Mutant StrainsMultiple SclerosisSequence Analysis, RNAMicrogliaOxidative StressNeurogenic InflammationGene Expression ProfilingMiceGene Regulatory NetworksHigh-Throughput Screening AssaysSingle-Cell Analysis

Keywords

NeuroinflammationOxidative stressProfiling (computer programming)Computational biologyBiologyBioinformaticsInflammationImmunologyComputer scienceBiochemistryInbred C57BL (mesh)High-Throughput Screening Assays (mesh)Neurogenic Inflammation (mesh)NeurodegenerativeInbred C57BLAntioxidantsMiceMultiple Sclerosis (mesh)Brain Disorders (rcdc)Animals (mesh)2.1 Biological and endogenous factorsInnateGene Regulatory NetworksAetiology32 Biomedical and Clinical Sciences (for-2020)3101 Biochemistry and cell biology (for-2020)EncephalomyelitisNeurosciences (rcdc)Neurodegenerative (rcdc)Humans (mesh)Generic health relevance (hrcs-hc)Mice (mesh)Experimental (mesh)Mutant StrainsGene Regulatory Networks (mesh)5.1 PharmaceuticalsNeurologicalRNA (mesh)FemaleMicrogliaDevelopment of treatments and therapeutic interventionsNeurogenic InflammationSingle-Cell AnalysisMutant Strains (mesh)Sequence AnalysisBiotechnologyImmunology (science-metrix)Encephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisOxidative Stress (mesh)1.1 Normal biological development and functioningIsoxazoles (mesh)6101107 Immunology (for)Antioxidants (mesh)Biotechnology (rcdc)ArticleExperimental5.1 Pharmaceuticals (hrcs-rac)GeneticsAnimalsHumans3204 Immunology (for-2020)Animal (mesh)1.1 Normal biological development and functioning (hrcs-rac)Biomedical and Clinical SciencesGenetics (rcdc)Neurological (hrcs-hc)AnimalSequence Analysis, RNAGene Expression ProfilingHuman GenomeNeurosciencesImmunityMicroglia (mesh)2.1 Biological and endogenous factors (hrcs-rac)IsoxazolesHuman Genome (rcdc)Gene Expression Profiling (mesh)Immunity, InnateMice, Mutant StrainsBrain DisordersHigh-Throughput Screening AssaysSingle-Cell Analysis (mesh)Mice, Inbred C57BLDisease Models, AnimalFemale (mesh)Biochemistry and cell biologyDisease ModelsRNAInnate (mesh)Generic health relevanceAutoimmune

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Single-cell transcriptomic analysis of the immune cell landscape in the aged mouse brain after ischemic stroke

10.6084/m9.figshare.19549871.v1figshare

Additional file 2 of Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation

10.6084/m9.figshare.26706933.v1figshare

Additional file 2 of Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation

10.6084/m9.figshare.26706933figshare

Additional file 1 of Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation

10.6084/m9.figshare.26706930figshare

Additional file 1 of Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation

10.6084/m9.figshare.26706930.v1figshare

Additional file 1 of Single-cell transcriptomic analysis of the immune cell landscape in the aged mouse brain after ischemic stroke

10.6084/m9.figshare.19549871figshare

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