A microRNA expression and regulatory element activity atlas of the mouse immune system is a dataset published in Nature Immunology (2021). On theSindex it has a DataRank of 1.4, placing it in the top 14.7% of the data-sharing corpus. It has been cited 38 times, with 33 citing works in its 1-hop citation network. Its calibrated FAIR score is 63/100.
Ranks in the top 15% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
The identifier 'GSE144081' is a GEO accession, which is a persistent identifier scheme accepted by the rubric.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
GEO (Gene Expression Omnibus) is a named data repository recognised in the rubric.
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
The GEO accession appears only in the body text (Data Availability section), not in the reference list.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“Data that support the findings of this study are available on the ImmGen website (www.immgen.org), and raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
The statement points to a repository record (GEO with accession), which is Colavizza category 3.
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“Threshold cycle (Ct) values of expression were converted to linear units (AU) by calibrating to the limit of reliable detection as determined by a standard curve of 10 different synthetic miRNAs and by inter-replicate variability (Extended Data Fig. 1a,b, Supplementary Table 1).”
The dataset content is described in running prose, not in an itemised inventory. [majority verdict 'partial' (3/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“Data that support the findings of this study are available on the ImmGen website (www.immgen.org), and raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
The data are stated to be available at a repository (GEO) with no stated precondition such as embargo, registration, or application.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“raw and processed miRNA expression data including sample metadata are available at GEO accession GSE144081.”
The paper describes the access route but does not label the access level with an explicit term. [majority verdict 'partial' (3/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The study uses only mouse cells, not human subjects, and no gatekeeper is mentioned for the data.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
The paper does not state how long the data will be retained or provide any persistence commitment. [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file format token (e.g., CSV, FASTQ) is named for the released data in the paper.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No community standard (e.g., MIAME, MINSEQE, or an ontology) is named in the paper for the data.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“Histone mark ChIP-seq datasets from Lavin et al78 (BioProject Accession: PRNJA267535)”
The paper provides an identifier for an external resource (BioProject accession PRNJA267535) used in the analysis. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No reuse licence or terms-of-use document is named for the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
Neither a version token nor a date is provided to identify the snapshot of the data.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“Code for normalization and batch correction of qPCR data is available at https://github.com/srose89/ImmGen-miRNA.”— not found in the paper; verdict downgraded
A machine-resolvable locator (GitHub repository URL) is given for the study's own code. [downgraded to 'partial' — no verifiable quote from the paper]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“B.D.B. was supported by NIH R01AI113221”
The paper provides a specific grant number (R01AI113221) attached to a named funder.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“miRNA profiling was performed by qPCR array to measure the expression of 923 different miRNAs.”
The paper names the specific method and platform used for data production. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (e.g., README, data dictionary) is named as accompanying the data, and no variable-definition table is present inside the article. [majority verdict 'no' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.550
From this paper's citation signal
Citation Network Contribution
0.858
From 27 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 33 citers.
U.S. Department of Health & Human Services | National Institutes of Health
Grant: R01AT011326
U.S. Department of Health & Human Services | National Institutes of Health
Grant: R01CA257195
U.S. Department of Health & Human Services | National Institutes of Health
Grant: R01CA254104
U.S. Department of Health & Human Services | National Institutes of Health
Grant: DP2HL151353
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
Grant: T32AI007605
National Institutes of Health
Grant: 5R24AI072073-19
ImmGen: Gene Expression and Regulation in Immune Cells
National Institutes of Health
Grant: 5R01CA257195-04
Deciphering the molecular control of intratumoral dendritic cells
National Institutes of Health
Grant: 5R01AT011326-03
Development of a platform for spatial functional genomics
National Institutes of Health
Grant: 5R01CA254104-03
Investigating Macrophage Molecular and Functional Diversity in Tumor Immunity
National Institutes of Health
Grant: 5T32AI007605-09
Immunology Training Grant
National Institutes of Health
Grant: 1R01AI113221-01A1
Modulating Immunity to Nucleic Acids and Inducing Tolerance by Gene Transfer
National Institutes of Health
Grant: 1DP2HL151353-01
Single-cell epigenomic and cellular plasticity
NIAID NIH HHS
Grant: R01 AI113221
NIAID NIH HHS
Grant: R24 AI072073
FWCI
2.22
Citation Percentile
0.9%
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals
Additional file 1 of Optimized workflow to modify microRNA expression in primary human intravascular cells
Additional file 1 of Optimized workflow to modify microRNA expression in primary human intravascular cells