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Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

Nature Medicine(2021)10.1038/s41591-021-01371-0Source: DataRank Database

Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection is a research paper published in Nature Medicine (2021). On theSindex it has a DataRank of 4.7. It has been cited 194 times, with 139 citing works in its 1-hop citation network.

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4.7DataRank · unranked

Scored on demand from live citation data

Open Access194 citations · 139 citing works in its network

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DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (31 grants)Impact (FWCI 10.87)OA: bronzeTopics (87)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 17%Citation Network 83%

Base Score Contribution

0.791

From this paper's citation signal

Citation Network Contribution

3.9

From 111 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 139 citers.

Loss of Y chromosome at the interface between aging and Alzheimer’s disease
Cellular and Molecular Life Sciences202112 citations14 referencesContributes 0.183
The vicious and virtuous circles of clonal hematopoiesis
Nature Medicine20219 citations13 referencesContributes 0.177
A Novel Method for Acquired Sex Chromosome Mosaicism
Advanced Biology20243 citations8 referencesContributes 0.173
Clonal hematopoiesis is not significantly associated with COVID-19 disease severity
Blood202225 citations23 referencesContributes 0.142
Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers
JAMA Network Open202317 citations25 referencesContributes 0.116

Authors (100)

Shu‐Hong Lin ORCID,Alexander G. Bick ORCID,Aoxing Liu ORCID,Kaavya Paruchuri ORCID,Chen Wang ORCID

Live enrichment

PubMed:34099924 PMC:PMC8245201 OpenAlex:https://openalex.org/W3170166010

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

Grant: 1F30HL149180-01

Dissecting the impact of clonal hematopoiesis on atherosclerosis using multiscale 'omics

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

Grant: 5-T32HL007208-43

U.S. Department of Health & Human Services | National Institutes of Health

Grant: UL1TR001873

NIH HHS

Grant: DP5 OD029586

NHLBI NIH HHS

Grant: K24 HL105780

NHLBI NIH HHS

Grant: F30 HL149180

NHLBI NIH HHS

Grant: R01 HL128914

NIMH NIH HHS

Grant: R01 MH104964

NIGMS NIH HHS

Grant: T32 GM136651

NHLBI NIH HHS

Grant: R01 HL148050

NHLBI NIH HHS

Grant: R01 HL151283

NHLBI NIH HHS

Grant: R01 HL092577

NIEHS NIH HHS

Grant: DP2 ES030554

NHLBI NIH HHS

Grant: T32 HL007208

NHGRI NIH HHS

Grant: R01 HG006855

NHLBI NIH HHS

Grant: R01 HL148565

National Institutes of Health

Grant: 5K24HL105780-07

Mentoring in Arrhythmia Research

National Institutes of Health

Grant: 1R01HL128914-01

AFGen Consortium: Atrial Fibrillation Genomics to Functional Analyses

National Institutes of Health

Grant: 5R01HG006855-02

Multi-allelic copy number variation of the human genome

National Institutes of Health

Grant: 1DP2ES030554-01

Revealing somatic genome alterations and their clinical sequelae: Ultrasensitive computational detection of mosaic structural variants

National Institutes of Health

Grant: 5T32HL007208-38

Cell & Molecular Training for Cardiovascular Biology

National Institutes of Health

Grant: 3T32GM136651-02S2

Medical Scientist Training Program

National Institutes of Health

Grant: 1R01HL148565-01

Clonal hematopoiesis in the Women's Health Initiative

National Institutes of Health

Grant: 5R01HL148050-04

Clonal hematopoiesis in humans: determinants of development and progression

National Institutes of Health

Grant: 5R01HL092577-02

Identification of common genetic variants for atrial fibrillation and PR interval

National Institutes of Health

Grant: 5R01MH104964-04

African Ancestry Genomic Psychiatry Cohort

National Institutes of Health

Grant: 3UL1TR001873-07S1

Clinical and Translational Science Award

Burroughs Wellcome Fund

Fondation Leducq

Howard Hughes Medical Institute

FWCI

10.87

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: Springer Nature TDM

journalhttps://www.nature.com/articles/s41591-021-01371-0.pdf

publisherhttps://www.nature.com/articles/s41591-021-01371-0.pdf

publisherhttps://www.nature.com/articles/s41591-021-01371-0

journalhttps://doi.org/10.1038/s41591-021-01371-0

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34099924

Fields of Study

Immune Cell Function and InteractionAcute Myeloid Leukemia ResearchEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciences0303 health sciencesAdolescentAdultAgedAged, 80 and overAgingBiological Specimen BanksChromosome AberrationsCommunicable DiseasesDigestive System DiseasesFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHematologic NeoplasmsHumansMaleMiddle AgedMosaicismPneumoniaRisk FactorsSepsisUrogenital AbnormalitiesYoung AdultGenitourinary Tract Anomalies

MeSH Terms

AdolescentAdultAgedAged, 80 and overAgingChromosome AberrationsCommunicable DiseasesDigestive System DiseasesFemaleGenotypeHumansMaleMiddle AgedMosaicismPneumoniaRisk FactorsUrogenital AbnormalitiesBiological Specimen BanksSepsisHematologic NeoplasmsGenetic Predisposition to DiseaseGenome-Wide Association StudyYoung Adult

Keywords

BiologyGenotypingImmunologySepsisPneumoniaHazard ratioInternal medicineMedicineGenotypeConfidence intervalGeneticsAdultMaleAgingAdolescentDigestive System Diseases610Genetics and Molecular BiologyCommunicable DiseasesGeneral Biochemistry, Genetics and Molecular BiologyRisk FactorsHumansGenetic Predisposition to DiseaseAgedBiological Specimen BanksAged, 80 and overChromosome AberrationsMosaicismGeneral MedicineMiddle AgedHematologic NeoplasmsGeneral BiochemistryFemaleGenome-Wide Association Study

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

10.6084/m9.figshare.22599859.v1figshare

Additional file 1 of Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

10.6084/m9.figshare.22599859figshare

Additional file 1 of Impact of clonal hematopoiesis in COVID-19 patients at high risk for adverse clinical outcomes

10.6084/m9.figshare.24225240.v1figshare

Additional file 1 of Impact of clonal hematopoiesis in COVID-19 patients at high risk for adverse clinical outcomes

10.6084/m9.figshare.24225240figshare

Additional file 2 of Impact of clonal hematopoiesis in COVID-19 patients at high risk for adverse clinical outcomes

10.6084/m9.figshare.24225247.v1figshare