Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures is a dataset published in Nature Methods (2024). On theSindex it has a DataRank of 0.626, placing it in the top 31.6% of the data-sharing corpus. It has been cited 21 times, with 18 citing works in its 1-hop citation network. Its calibrated FAIR score is 56/100.
Ranks in the top 32% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“Genomics 2 Proteins portal (https://g2p.broadinstitute.org/):”
The paper provides the portal URL as the data location, but no persistent identifier (DOI, Handle, ARK, etc.) is given.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“Genomics 2 Proteins portal (https://g2p.broadinstitute.org/):”
The data are held by the G2P portal website, which is not a repository listed in re3data/FAIRsharing.
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“Genomics 2 Proteins portal (https://g2p.broadinstitute.org/):”
The dataset identifier (the portal URL) appears only in the body text, not in the reference list.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All resources in this paper are available on the G2P portal website (https://g2p.broadinstitute.org/).”
The data availability statement points to the portal website, not a repository record with an accession or DOI.
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“As of October 2023, the API links 20,292 human genes that encode 20,242 UniProtKB proteins corresponding to 42,413 isoforms, via 53,607 Ensembl transcripts and 57,543 RefSeq transcripts, to 77,923 protein structures (58,027 PDB structures and 19,896 AlphaFold structures).”
The dataset's content and size are stated in running prose, not in an itemised inventory (section, table, or list). [majority verdict 'partial' (4/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“All resources in this paper are available on the G2P portal website (https://g2p.broadinstitute.org/).”
The data are stated to be available on the portal without any precondition.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“All resources in this paper are available on the G2P portal website (https://g2p.broadinstitute.org/).”
No access-level label is applied, but the data availability statement describes an action (go to the website). [majority verdict 'partial' (4/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are not sensitive human-subject data; no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“All resources in this paper are available on the G2P portal website.”— not found in the paper; verdict downgraded
The data are stated to be available now, but no persistence commitment is given. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“download annotated protein sequence (CSV/TSV file) and structure (PyMOL-compatible file) for downstream analysis”
The paper names CSV, TSV, and PDB (PyMOL-compatible) as open formats for the data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“We utilized DSSP to annotate both three-class and nine-class secondary structures on AlphaFold structures.”
The paper names DSSP, a community standard for secondary structure annotation, as applied to the data. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“human reference genome GRCh38”
The paper references the GRCh38 assembly as an identifier for the external resource used. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No licence is stated for the data; the article's CC-BY-NC-ND licence applies to the paper, not the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“as of October 2023”
The paper pins the snapshot with a date (October 2023) but gives no version token for the study's own data. [majority verdict 'partial' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“An open-source Python library and command line tool for data access via the portal APIs is available at https://github.com/broadinstitute/g2papi/.”— not found in the paper; verdict downgraded
A GitHub URL is given as a machine-resolvable locator for the code. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“UM1HG011969”
Award/grant numbers are provided for the funding. [majority verdict 'yes' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“We utilized DSSP to annotate both three-class and nine-class secondary structures on AlphaFold structures.”
The paper names a specific tool (DSSP) used to produce the data annotations. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Protein features in the G2P portal”
Variable definitions are provided inside the article (in the 'Protein features' section), not in a separate documentation file deposited with the data. [majority verdict 'partial' (4/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.464
From this paper's citation signal
Citation Network Contribution
0.162
From 10 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 18 citers.
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
Grant: UM1HG011969
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
Grant: RM1HG010461
Merkin Institute for Transformative Technologies in Healthcare
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
FWCI
3.40
Citation Percentile
0.9%
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals