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TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model

Nature Neuroscience(2024)10.1038/s41593-024-01777-2Source: DataRank Database

TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model is a research paper published in Nature Neuroscience (2024). On theSindex it has a DataRank of 0.489. It has been cited 25 times.

N/A

0.489DataRank · unranked

Scored on demand from live citation data

Open Access25 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 5.80)OA: hybridTopics (57)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.489

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (10)

Bakhos Tadros,Yan Hong Wei Liang,Young Doo Kim ORCID,Cristian A. Lasagna‐Reeves ORCID,Jun Young Sonn ORCID

Live enrichment

PubMed:39528671 PMC:PMC11614740 OpenAlex:https://openalex.org/W4404224704

JPB Foundation

Grant: N/A

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

Grant: 1R01NS119280

NIA NIH HHS

Grant: P30 AG066507

NINDS NIH HHS

Grant: P50 NS038377

NIA NIH HHS

Grant: U19 AG033655

NIA NIH HHS

Grant: P30 AG062421

NICHD NIH HHS

Grant: P50 HD103555

NINDS NIH HHS

Grant: R01 NS119280

National Institutes of Health

Grant: 5U19AG033655-12

Biomarkers of Cognitive Decline Among Normal Individuals: The Biocard Cohort

National Institutes of Health

Grant: 5P30AG062421-03

Massachusetts Alzheimer's Disease Research Center

National Institutes of Health

Grant: 5P50NS038377-03

CORE--TRANSGENIC AND NEUROBEHAVIOR FACILITY

National Institutes of Health

Grant: 5R01NS119280-02

Tau-seed protein interactome and its role in neurodegenerative tauopathies

National Institutes of Health

Grant: 1P50HD103555-01

Baylor College of Medicine Intellectual and Developmental Disabilities Research Center

National Institutes of Health

Grant: 5P30AG066507-03

Johns Hopkins Alzheimer's Disease Research Center

Howard Hughes Medical Institute

FWCI

5.80

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.nature.com/articles/s41593-024-01777-2.pdf

publisherhttps://www.nature.com/articles/s41593-024-01777-2.pdf

publisherhttps://www.nature.com/articles/s41593-024-01777-2

journalhttps://doi.org/10.1038/s41593-024-01777-2

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39528671

Fields of Study

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AnimalsDisease Models, AnimalHumansMice, TransgenicPhosphorylationtau ProteinsTauopathiesMiceTYK2 KinaseProtein Aggregation, Pathological

Keywords

TauopathyNeurosciencePhosphorylationBiologyNeurodegenerationCell biologyDiseaseMedicineInternal medicine570Medical Sciences610tau ProteinsMice, TransgenicMolecular neuroscienceProtein Aggregation, PathologicalTransgenicArticleBiomedical InformaticsMicePathologicalMedical SpecialtiesMedicine and Health Sciencesand ImmunityAnimalsHumansBiological PhenomenaTYK2 KinaseAnimalCell PhenomenaICTS (Institute of Clinical and Translational Sciences)NeurosciencesLife SciencesGenetics and GenomicsAlzheimer's diseaseProtein AggregationDisease Models, AnimalTauopathiesMedical Molecular BiologyDisease ModelsMedical Genetics

Sustainable Development Goals

SDG 0: Good health and well-being