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Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas

Scientific Reports(2021)10.1038/s41598-021-85589-5Source: DataRank Database

Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas is a research paper published in Scientific Reports (2021). On theSindex it has a DataRank of 0.241. It has been cited 4 times.

N/A

0.241DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.24)OA: goldTopics (83)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (11)

Jun Jeon,Lillian Sun ORCID,Adeeb Derakhshan ORCID,Jianhong Chen ORCID,Sophie G. Carlson

Live enrichment

PubMed:33737574 PMC:PMC7973748 OpenAlex:https://openalex.org/W3139321916

National Institue on Deafness and Other Communication Disorders

Grant: Intramural Research Program, projects ZIA-DC-000016, 73 and 74

Intramural NIH HHS

Grant: ZIA DC000016

National Institutes of Health

Grant: 1ZIADC000016-26

NF-kappaB in pathogenesis and therapy of head and neck cancer

National Institutes of Health

FWCI

0.24

Citation Percentile

0.4%

Citation Trend

2023

2024

2025

goldLicense: cc-by

journalhttps://www.nature.com/articles/s41598-021-85589-5.pdf

publisherhttps://www.nature.com/articles/s41598-021-85589-5.pdf

publisherhttps://www.nature.com/articles/s41598-021-85589-5

journalhttps://doi.org/10.1038/s41598-021-85589-5

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33737574

Fields of Study

NF-κB Signaling PathwaysCell death mechanisms and regulationinterferon and immune responses0301 basic medicine03 medical and health sciences0303 health sciencesAntineoplastic AgentsApoptosisBaculoviral IAP Repeat-Containing 3 ProteinCaspase 8Cell DeathCell Line, TumorDNA Copy Number VariationsDipeptidesFemaleGene Expression Regulation, NeoplasticHumansIndolesInhibitor of Apoptosis ProteinsMalePapillomaviridaePapillomavirus InfectionsReceptors, TNF-Related Apoptosis-Inducing LigandSquamous Cell Carcinoma of Head and NeckTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alpha

MeSH Terms

Baculoviral IAP Repeat-Containing 3 ProteinSquamous Cell Carcinoma of Head and NeckAntineoplastic AgentsDipeptidesFemaleHumansIndolesMaleTumor Necrosis Factor-alphaGene Expression Regulation, NeoplasticCell DeathApoptosisPapillomaviridaePapillomavirus InfectionsCell Line, TumorInhibitor of Apoptosis ProteinsCaspase 8Receptors, TNF-Related Apoptosis-Inducing LigandTNF-Related Apoptosis-Inducing LigandDNA Copy Number Variations

Keywords

Head and neckAgonistMedicineAntibodyHead and neck squamous-cell carcinomaCancer researchInternal medicineOncologyPathologyReceptorImmunologyHead and neck cancerCancerMaleIndolesDNA Copy Number VariationsScienceAntineoplastic AgentsApoptosisArticleInhibitor of Apoptosis ProteinsTNF-Related Apoptosis-Inducing LigandCell Line, TumorHumansPapillomaviridaeCaspase 8Cell DeathSquamous Cell Carcinoma of Head and NeckTumor Necrosis Factor-alphaQPapillomavirus InfectionsRDipeptidesBaculoviral IAP Repeat-Containing 3 ProteinGene Expression Regulation, NeoplasticReceptors, TNF-Related Apoptosis-Inducing LigandFemale

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being