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The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains

Scientific Reports(2024)10.1038/s41598-024-65248-1Source: DataRank Database

The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains is a research paper published in Scientific Reports (2024). On theSindex it has a DataRank of 0. It has been cited 53 times.

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Open Access53 citations

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Enrichment:Funding (9 grants)Impact (FWCI 9.20)OA: goldTopics (127)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Judith Camats‐Perna ORCID,Estella A. Newcombe ORCID,Tessa Onraet ORCID,Daniel Campbell ORCID,Josiah T. Sucic

Live enrichment

PubMed:38906984 PMC:PMC11192733 OpenAlex:https://openalex.org/W4399906597

Department of Health | National Health and Medical Research Council

Grant: GNT1128436

Impact of interleukin-18 on Alzheimer’s disease

Department of Health | National Health and Medical Research Council

Grant: GNT1129192

Investigating interleukin-37 as a treatment and biomarker for Alzheimer’s disease

Department of Health | National Health and Medical Research Council

Grant: GNT1139469

Targeting inflammation as a biomarker and treatment for Alzheimer's disease

U.S. Department of Health & Human Services | National Institutes of Health

Grant: 1P30AG066519-01

The Alzheimer's Disease Research Center at the University of California, Irvine

National Health and Medical Research Council (NHMRC)

Grant: 1129192

Investigating interleukin-37 as a treatment and biomarker for Alzheimer’s disease

National Health and Medical Research Council (NHMRC)

Grant: 1139469

Targeting inflammation as a biomarker and treatment for Alzheimer's disease

National Institutes of Health

Grant: 1R21AG069081-01

NF-ÎºB as a driver of neurotoxic astrocytes in Alzheimers disease

National Health and Medical Research Council (NHMRC)

Grant: 1128436

Impact of interleukin-18 on Alzheimer’s disease

Clem Jones Foundation

FWCI

9.20

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1038/s41598-024-65248-1

publisherhttps://doi.org/10.1038/s41598-024-65248-1

publisherhttps://www.nature.com/articles/s41598-024-65248-1.pdf

publisherhttps://www.nature.com/articles/s41598-024-65248-1

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38906984

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsImmune Response and Inflammation0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsFemaleHumansMaleMiceAlzheimer DiseaseAmyloid beta-PeptidesAstrocytesBrainDisease Models, AnimalGlial Fibrillary Acidic ProteinNF-kappa BSignal TransductionNF-kappa B p50 Subunit

MeSH Terms

Alzheimer DiseaseAnimalsAstrocytesBrainDisease Models, AnimalFemaleGlial Fibrillary Acidic ProteinHumansMaleSignal TransductionAmyloid beta-PeptidesNF-kappa BMiceNF-kappa B p50 Subunit

Keywords

Glial fibrillary acidic proteinAstrocyteNF-κBNeuroprotectionBiologyCell biologyMicrogliaNFKB1Alzheimer's diseaseNeuroinflammationAquaporin 4Amyloid precursor proteinAmyloid betaTumor necrosis factor alphaNeuroscienceInflammationSignal transductionTranscription factorImmunologyMedicineDiseaseCentral nervous systemBiochemistryPathologyImmunohistochemistryMaleAgingNeurodegenerativeAcquired Cognitive Impairment (rcdc)Aging (rcdc)MiceBrain Disorders (rcdc)Amyloid beta-Peptides (mesh)Dementia (rcdc)Astrocytes (mesh)2.1 Biological and endogenous factorsAnimals (mesh)Male (mesh)Neurosciences (rcdc)Neurodegenerative (rcdc)Alzheimer Disease (mesh)Humans (mesh)Alzheimer's Disease (rcdc)QRNF-kappa BMice (mesh)BrainBiological SciencesCognitive DeclineUp-RegulationNeurologicalNecrosis-Factor-AlphaFemaleGlial Fibrillary Acidic Protein (mesh)5701.1 Normal biological development and functioningScienceGene-ExpressionActivationArticleBrain (mesh)Alzheimer DiseaseAcquired Cognitive ImpairmentAnimalsHumansAnimal (mesh)1.1 Normal biological development and functioning (hrcs-rac)31 Biological Sciences (for-2020)Mouse ModelAmyloid beta-PeptidesAnimalNeurological (hrcs-hc)Autoimmune EncephalomyelitisNeurosciencesAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)BetaNF-kappa B p50 SubunitInos Expression2.1 Biological and endogenous factors (hrcs-rac)Brain Disorders3101 Biochemistry and Cell Biology (for-2020)Glutamate TransporterDisease Models, AnimalFemale (mesh)1000 GeneralAstrocytesDisease ModelsSignal Transduction (mesh)DementiaAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) (rcdc)Biochemistry and Cell BiologyNF-kappa B (mesh)

The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains

FAIR Checklist

Authors (12)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)