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A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivo

Communications Biology(2023)10.1038/s42003-023-04860-9Source: DataRank Database

A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivo is a research paper published in Communications Biology (2023). On theSindex it has a DataRank of 0. It has been cited 19 times.

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0DataRank · unranked

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Open Access19 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 3.15)OA: goldTopics (53)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Graeme Walker Lindsey,Yusuke Higuchi ORCID,Yumi Itoh ORCID,Tatsuya Suzuki ORCID,Toru Okamoto ORCID

Live enrichment

PubMed:37173421 PMC:PMC10177734 OpenAlex:https://openalex.org/W4376273985

NCATS NIH HHS

Grant: UL1 TR002003

NIGMS NIH HHS

Grant: P20 GM103446

NIMHD NIH HHS

Grant: U54 MD015959

National Science Foundation

Grant: 2122158

Partnership for Research and Education in Soft Matter Research & Technology and Quantum Confinement Materials Design (SMaRT QD)

National Institutes of Health

Grant: 5P20GM103446-15

Bioinformatics Core

National Institutes of Health

Grant: 5UL1TR002003-08

Clinical and Translational Science Award

FWCI

3.15

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.nature.com/articles/s42003-023-04860-9.pdf

publisherhttps://www.nature.com/articles/s42003-023-04860-9.pdf

publisherhttps://www.nature.com/articles/s42003-023-04860-9

journalhttps://doi.org/10.1038/s42003-023-04860-9

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37173421

Fields of Study

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesMonoclonal and Polyclonal Antibodies Research0301 basic medicine03 medical and health sciencesHumansAngiotensin-Converting Enzyme 2Antibodies, MonoclonalCOVID-19SARS-CoV-2Protein EngineeringSpike Glycoprotein, CoronavirusSARS-CoV-2 variants

MeSH Terms

Angiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Antibodies, MonoclonalHumansProtein EngineeringSpike Glycoprotein, Coronavirus

Keywords

DecoyIn vivoIn vitroChemistryMonoclonal antibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Computational biologyCoronavirus disease 2019 (COVID-19)VirologyMolecular biologyBiologyAntibodyBiochemistryGeneticsReceptorMedicineMedical SciencesQH301-705.5SARS-CoV-2monoclonal610Antibodies, MonoclonalCOVID-19protein engineering600Medical BiochemistryArticleangiotensin-converting enzyme 2Spike Glycoprotein, CoronavirusMedicine and Health SciencesantibodiesHumansBiology (General)

Sustainable Development Goals

SDG 0: Good health and well-being

A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivo

FAIR Checklist

Authors (9)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)