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OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies

Communications Biology(2025)10.1038/s42003-025-08534-6Source: DataRank Database

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies is a research paper published in Communications Biology (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.92)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Yiqi Wang ORCID,Yong‐hui Jiang ORCID,Ryan Donahue ORCID,Gaby Cao,Weixuan Yan

Live enrichment

PubMed:41102382 PMC:PMC12533019 OpenAlex:https://openalex.org/W4415249068

U.S. Department of Health & Human Services | NIH | National Eye Institute

Grant: EY032181

NEI NIH HHS

Grant: K99 EY032181

NEI NIH HHS

Grant: R00 EY032181

FWCI

0.92

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by-nc-nd

journalhttps://www.nature.com/articles/s42003-025-08534-6.pdf

publisherhttps://www.nature.com/articles/s42003-025-08534-6.pdf

publisherhttps://www.nature.com/articles/s42003-025-08534-6

journalhttps://doi.org/10.1038/s42003-025-08534-6

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41102382

Fields of Study

Glaucoma and retinal disordersNeuroinflammation and Neurodegeneration MechanismsRetinal Diseases and TreatmentsRetinal Ganglion CellsAnimalsMembrane Transport ProteinsMiceCell Cycle ProteinsOptic Nerve DiseasesNeuroinflammatory DiseasesMice, KnockoutMice, Inbred C57BLDisease Models, AnimalTranscription Factor TFIIIAGlaucomaHumansMale

MeSH Terms

Neuroinflammatory DiseasesAnimalsDisease Models, AnimalGlaucomaHumansMaleMice, Inbred C57BLOptic Nerve DiseasesRetinal Ganglion CellsMice, KnockoutCell Cycle ProteinsMembrane Transport ProteinsTranscription Factor TFIIIAMice

Keywords

OptineurinNeuroinflammationRetinal ganglion cellNeuroprotectionDownregulation and upregulationRetinaNeurodegenerationPathogenesis

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies

FAIR Checklist

Authors (14)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)