Human Cell Aging Transcriptome Atlas (HCATA): a single-cell atlas of age-associated transcriptomic alterations across human tissues is a dataset published in Communications Biology (2025). On theSindex it has a DataRank of 0.212, placing it in the top 63.4% of the data-sharing corpus. It has been cited 3 times, with 2 citing works in its 1-hop citation network. Its calibrated FAIR score is 46/100.
Ranks in the top 63% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“HCATA is publicly accessible at http://hcata-xiaodonglab.org:3304”
The only identifier given for the dataset is a plain HTTP URL, not a DOI, Handle, ARK, URN, or repository accession, so it is a web address without a persistent identifier scheme.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“HCATA is publicly accessible at http://hcata-xiaodonglab.org:3304”
The data are hosted on a lab website (hcata-xiaodonglab.org), not a named repository from the approved list (e.g., GEO, SRA, Zenodo) or a re3data-registered archive.
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“All data is available for download and exploration at http://hcata-xiaodonglab.org:3304”
The dataset's identifier (the URL) appears only in the body text, not as a reference-list entry.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All data is available for download and exploration at http://hcata-xiaodonglab.org:3304”
The statement points to a URL (not a repository record with a persistent identifier), placing it in Colavizza category 3 as a link to archived data, but the URL is not a repository record with an accession/DOI, so it is classed as partial per the rubric.
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“HCATA, contains single-cell RNA-sequencing datasets from 76 publications totaling 92 million cells and 3,475 tissue-level samples across more than 50 tissue types with ages ranging from 0 to 103 years”
The dataset's content is described in a running sentence rather than in a dedicated section, table, or enumerated list, so it is ordinary prose.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“HCATA is publicly accessible at http://hcata-xiaodonglab.org:3304”
The text states the data are publicly accessible with no stated precondition, embargo, or registration requirement.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“HCATA is publicly accessible at http://hcata-xiaodonglab.org:3304”
The sentence 'HCATA is publicly accessible' uses the natural-language label 'publicly accessible', which is equivalent to 'open access' from the standard access-rights vocabulary.
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The paper aggregates public human scRNA-seq data and does not mention any gatekeeper, institution, or personal contact for access to the data.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“All data is available for download and exploration at http://hcata-xiaodonglab.org:3304”
The sentence indicates current availability ('available') but does not commit to any retention period or permanent archival, so only timing is stated.
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“Raw scRNA-seq count matrices were stored in a matrix mart file format which consists of three files: a barcode file, feature file, and matrix file.”— not found in the paper; verdict downgraded
Matrix mart (MTX) is a community-standard open format for single-cell RNA-seq data. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“Gene Ontology (GO) term enrichment”
The paper names Gene Ontology, a community-standard ontology registered in FAIRsharing, as the vocabulary used for the data analysis. [majority verdict 'yes' (4/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
No identifier (DOI, accession, RRID, etc.) for any external resource is provided; only bare names like 'GenAge database' and 'Cell Marker' appear.
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
The only license mentioned is for the article (CC BY-NC-ND 4.0), not for the data; no reuse license or terms are stated for the dataset itself.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is given for the dataset; the paper only mentions that future updates will occur, without pinning the current snapshot.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
The paper describes a standard processing pipeline but does not provide any code repository URL, DOI, or supplementary code; code availability is not addressed.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This work was supported by NIH grants R00 AG056656 (X.D.), U19 AG056278 (X.D.), P01 AI172501 (X.D.), U54 AG076041 (X.D.), U54 AG079754 (X.D.), R35 GM159832 (L.Z.), and T32 AG029796 (J.B.)”
Specific award numbers (R00, U19, P01, etc.) are provided for the funding agencies.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“InnoDB (version 8.0.3) as its engine and MySQL (version 8.0.3) as its DBMS”— not found in the paper; verdict downgraded
The paper names specific software and versions (InnoDB, MySQL, Angular, IGV, etc.) used to produce and host the data. [downgraded to 'partial' — no verifiable quote from the paper]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (README, data dictionary, codebook) is named as accompanying the data; the metadata are described as stored in a table but not as a separate documentation file.
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.208
From this paper's citation signal
Citation Network Contribution
4.27 × 10⁻³
From 1 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 2 citers.
U.S. Department of Health & Human Services | NIH | National Institute on Aging
Grant: U19 AG056278
NIGMS NIH HHS
Grant: R35 GM159832
U.S. Department of Health & Human Services | NIH | National Institute on Aging
Grant: T32 AG029796
NIA NIH HHS
Grant: U54 AG076041
NIA NIH HHS
Grant: U54 AG079754
NIA NIH HHS
Grant: R00 AG056656
NHLBI NIH HHS
Grant: P01 HL160476
NIAID NIH HHS
Grant: P01 AI172501
American Federation for Aging Research
Felser-Lampert Chair in Aging Studies is made possible through an endowment provided by David and Elizabeth Fesler.
FWCI
1.13
Citation Percentile
0.8%
Citation Trend
Fields of Study
MeSH Terms
Keywords