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Molecular mechanisms limiting the AAV gene therapy treatment window in mouse models of blue cone monochromacy

Communications Biology(2025)10.1038/s42003-025-09045-0Source: DataRank Database

Molecular mechanisms limiting the AAV gene therapy treatment window in mouse models of blue cone monochromacy is a research paper published in Communications Biology (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.00)OA: goldTopics (34)IDs (PubMed, PMC, OpenAlex)

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Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Emily Sechrest ORCID,Li Ma ORCID,Madyson Ashcraft,Tongju Guan,Robert J. Barbera

Live enrichment

PubMed:41286353 PMC:PMC12644701 OpenAlex:https://openalex.org/W4416594552

Foundation for the National Institutes of Health

Grant: R01 EY030056

Foundation for the National Institutes of Health

Grant: R01 EY025536

Foundation for the National Institutes of Health

Grant: R21 EY036144

Foundation for the National Institutes of Health

Grant: EY014800-039003

NIGMS NIH HHS

Grant: P20 GM144230

NEI NIH HHS

Grant: R01 EY008123

NIGMS NIH HHS

Grant: U54 GM104942

NIGMS NIH HHS

Grant: P20 GM103434

NIGMS NIH HHS

Grant: P20 GM121322

Research to Prevent Blindness

FWCI

0.00

Citation Percentile

0.2%

goldLicense: cc-by-nc-nd

journalhttps://www.nature.com/articles/s42003-025-09045-0.pdf

publisherhttps://www.nature.com/articles/s42003-025-09045-0.pdf

publisherhttps://www.nature.com/articles/s42003-025-09045-0

journalhttps://doi.org/10.1038/s42003-025-09045-0

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41286353

Fields of Study

Retinal Development and DisordersVirus-based gene therapy researchConnexins and lens biologyAnimalsDependovirusGenetic TherapyColor Vision DefectsMiceDisease Models, AnimalRetinal Cone Photoreceptor CellsMice, KnockoutGenetic VectorsRod OpsinsMice, Inbred C57BLBlue cone monochromatism

MeSH Terms

DependovirusAnimalsColor Vision DefectsDisease Models, AnimalGenetic VectorsMice, Inbred C57BLGenetic TherapyRod OpsinsRetinal Cone Photoreceptor CellsMice, KnockoutMice

Keywords

TransgeneGenetic enhancementLimitingCone (formal languages)GeneFunction (biology)Gene expressionPhenotype