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Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease

Nature Cardiovascular Research(2024)10.1038/s44161-024-00488-ySource: DataRank Database

Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease is a research paper published in Nature Cardiovascular Research (2024). On theSindex it has a DataRank of 1.1. It has been cited 48 times, with 40 citing works in its 1-hop citation network.

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1.1DataRank · unranked

Scored on demand from live citation data

Open Access48 citations · 40 citing works in its network

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DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (29 grants)Impact (FWCI 13.82)OA: hybridTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 54%Citation Network 46%

Base Score Contribution

0.584

From this paper's citation signal

Citation Network Contribution

0.497

From 25 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 40 citers.

Global, regional and national burden of depressive disorders in adolescents and young adults, 1990–2021: systematic analysis of the global burden of disease study 2021
Frontiers in Public Health202511 citations42 referencesContributes 0.059
Association between genetic liability to physical health conditions and comorbidities in individuals with severe mental illness: an analysis of two cross-sectional observational studies in the UK
The Lancet Psychiatry20255 citations36 referencesContributes 0.050
The Role of Energy Homeostasis in Depression Pathophysiology and Its Heterogeneity
JAMA Psychiatry20257 citations42 referencesContributes 0.050
Inflammatory index is a promising biomarker for maintenance hemodialysis patients with cardiovascular disease
European journal of medical research20247 citations48 referencesContributes 0.043
Association of systemic immune-inflammation index with all-cause and cardiovascular mortality among adults with depression: evidence from NHANES 2005–2018
BMC Psychiatry20256 citations48 referencesContributes 0.041

Authors (26)

Joëlle A. Pasman ORCID,Ziyan Ma ORCID,Arvid Harder ORCID,Shuyang Yao ORCID,Nadine Parker ORCID

Live enrichment

PubMed:39215135 PMC:PMC11182748 OpenAlex:https://openalex.org/W4399731249

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH)

Grant: MH124871

Lundbeck Foundation

Grant: R155-2014-1724

Lundbeck Foundation

Grant: R248-2017-2003

Wellcome Trust

Grant: 220857/Z/20/Z

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Marie Sklodowska-Curie Actions (H2020 Excellent Science - Marie Sklodowska-Curie Actions)

Grant: 801133

SCIENTIA-FELLOWS II: International Postdoctoral Fellowship Programme

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020)

Grant: 964874

Using real-world big data from eHealth, biobanks and national registries, integrated with clinical trial data to improve outcome of severe mental disorders

European Research Council

Grant: 101042183

Subtype as a key to reduce heterogeneity of treatment effects in major depressive disorder

NIMH NIH HHS

Grant: R01 MH123724

NIMH NIH HHS

Grant: R01 MH121545

NIMH NIH HHS

Grant: R01 MH124851

Vetenskapsrådet (Swedish Research Council)

Grant: D0886501

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH)

Grant: MH121545

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH)

Grant: MH123724

European Research Council

Grant: 101076686

Mental illness, substance use, and cardiovascular disease: Unravelling causal relationships

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020)

Grant: 847776

Predicting comorbid cardiovascular disease in individuals with mental disorder by decoding disease mechanisms

NIMH NIH HHS

Grant: R01 MH124871

National Institutes of Health

Grant: 5R01MH123724-02

A Trans-Nordic Study of Extreme Major Depression

The Research Council of Norway

Grant: 296030

A Trans-Nordic Study of Mood disorders (NOR-FREED)

UK Research and Innovation

Grant: MR/W014386/1

DATAMIND: Data Hub for Mental health INformatics research Development

The Research Council of Norway

Grant: 300309

Prediction of antipsychotic drug response; a personalised medicine approach in schizophrenia

Wellcome Trust

Grant: 220857

Exploiting genomic approaches to identify the environmental basis of depression

National Institutes of Health

Grant: 5R01MH121545-05

2/2 Genetics at an extreme: an efficient genomic study of individuals with clinically severe major depression receiving ECT

The Research Council of Norway

Grant: 223273

NORMENT; Norwegian Centre for Mental Disorders Research

National Institutes of Health

Grant: 1R01MH124851-01

2/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact

The Research Council of Norway

Grant: 324499

Polygenic and psychosocial interplay in brain development across mental disorders

National Institutes of Health

Grant: 5R01MH124871-05

1/7 PGC: Advancing Discovery and Impact

The Research Council of Norway

Grant: 326813

Preventing multimorbidity in severe mental disorders with a multidisciplinary approach

Wellcome Trust

FWCI

13.82

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1038/s44161-024-00488-y

publisherhttps://doi.org/10.1038/s44161-024-00488-y

publisherhttps://www.nature.com/articles/s44161-024-00488-y.pdf

publisherhttps://www.nature.com/articles/s44161-024-00488-y

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38898929

Fields of Study

Cardiac Health and Mental HealthTryptophan and brain disordersStress Responses and Cortisol0301 basic medicine0303 health sciences03 medical and health sciencesFemaleHumansMaleCardiovascular DiseasesComorbidityMajor Depressive DisorderGenetic Predisposition to DiseaseGenome-Wide Association StudyHeart Disease Risk FactorsRisk AssessmentRisk Factors

MeSH Terms

HumansCardiovascular DiseasesGenetic Predisposition to DiseaseRisk AssessmentRisk FactorsComorbidityFemaleMaleGenome-Wide Association StudyHeart Disease Risk FactorsMajor Depressive Disorder

Keywords

ComorbidityDiseaseMedicineSignature (topology)Major depressive disorderClinical psychologyPsychologyPsychiatryInternal medicineCognitionMaleRisk AssessmentArticleCardiovascular DiseasesHeart Disease Risk FactorsRisk FactorsHumansFemaleGenetic Predisposition to DiseaseGenome-Wide Association Study

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being