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A novel single nucleotide polymorphism and five probable haplotypes in the 5′ flanking region of the IL-6 gene in African-Americans

Genes & Immunity(1999)10.1038/sj.gene.6363652Source: DataRank Database

A novel single nucleotide polymorphism and five probable haplotypes in the 5′ flanking region of the IL-6 gene in African-Americans is a research paper published in Genes & Immunity (1999). On theSindex it has a DataRank of 2.9. It has been cited 40 times, with 36 citing works in its 1-hop citation network.

N/A

2.9DataRank · unranked

Scored on demand from live citation data

40 citations · 36 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 0.92)OA: closedTopics (33)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 19%Citation Network 81%

Base Score Contribution

0.557

From this paper's citation signal

Citation Network Contribution

2.4

From 34 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 36 citers.

The IL - 6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis
Journal of Cellular and Molecular Medicine200623 citations20 referencesContributes 0.159
IL-6 gene variation is not associated with increased serum levels of IL-6, muscle, weakness, or frailty in older women
Experimental Gerontology200565 citations27 referencesContributes 0.155
Interleukin 6 gene promoter polymorphism is not associated with Kawasaki disease
Genes and Immunity200120 citations21 referencesContributes 0.145
IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS)
Genes and Immunity200298 citations34 referencesContributes 0.135
Abnormal regulation of interleukin 6 in systemic juvenile idiopathic arthritis.
PubMed200160 citations32 referencesContributes 0.128

Authors (4)

J McNicholl,LW Moreland,S Louis Bridges,M Osiri

Live enrichment

PubMed:11196667 OpenAlex:https://openalex.org/W2327017833

PHS HHS

Grant: R01A-A44384

FWCI

0.92

Citation Percentile

0.7%

Citation Trend

2012

2014

2017

2019

closedLicense: https://www.springer.com/tdm

publisherhttps://www.nature.com/articles/6363652.pdf

publisherhttps://www.nature.com/articles/6363652

journalhttps://doi.org/10.1038/sj.gene.6363652

repositoryhttps://pubmed.ncbi.nlm.nih.gov/11196667

Fields of Study

NF-κB Signaling PathwaysImmune Response and InflammationCytokine Signaling Pathways and InteractionsBlack PeopleHaplotypesHumansInterleukin-6Polymorphism, Single NucleotidePromoter Regions, GeneticUnited StatesBlack or African American

MeSH Terms

Black or African AmericanHaplotypesHumansPromoter Regions, GeneticUnited StatesInterleukin-6Polymorphism, Single NucleotideBlack People

Keywords

HaplotypeBiologySingle-nucleotide polymorphismGeneticsSNP5' flanking regionAlleleGeneTag SNPAllele frequencyPolymorphism (computer science)GenotypePromoterGene expression