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The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor

Biochemical Journal(2024)10.1042/bcj20240626Source: DataRank Database

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor is a research paper published in Biochemical Journal (2024). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.73)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Yunpeng Bai ORCID,Sarah M. Cavender,Yiming Miao ORCID,Frederick Nguele Meke ORCID,Emily L. Lasse-Opsahl

Live enrichment

PubMed:39665584 PMC:PMC12198624 OpenAlex:https://openalex.org/W4405320448

HHS | National Institutes of Health

Grant: RO1CA069202

HHS | National Institutes of Health

Grant: RO1AG064250

HHS | National Institutes of Health

Grant: P30 CA023168

NIA NIH HHS

Grant: R01 AG064250

NCI NIH HHS

Grant: R01 CA069202

FWCI

0.73

Citation Percentile

0.7%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://portlandpress.com/biochemj/article-pdf/doi/10.1042/BCJ20240626/964723/bcj-2024-0626.pdf

HYBRIDhttps://doi.org/10.1042/bcj20240626

publisherhttps://portlandpress.com/biochemj/article-pdf/doi/10.1042/BCJ20240626/964723/bcj-2024-0626.pdf

publisherhttps://portlandpress.com/biochemj/article-pdf/482/07/341/964723/bcj-2024-0626.pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39665584

Fields of Study

MicroRNA in disease regulationRNA modifications and cancerProtein Tyrosine PhosphatasesMedicineBiology

MeSH Terms

HumansSignal TransductionDown-RegulationUp-RegulationGene Expression Regulation, NeoplasticProtein Tyrosine PhosphatasesMicroRNAsCell Line, TumorSTAT3 Transcription FactorPTEN PhosphohydrolaseJanus Kinase 2HEK293 Cells

Keywords

PTENDownregulation and upregulationPhosphataseCancer researchmicroRNAProtein tyrosine phosphataseSuppressorPhosphorylationBiologyTumor suppressor geneCell biologyCancerCarcinogenesisSignal transductionPI3K/AKT/mTOR pathwayGeneGeneticsStat3JAK2Mir-21Prl2

Sustainable Development Goals

SDG 0: Good health and well-being