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Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution

Gastroenterology(2020)10.1053/j.gastro.2020.01.027Source: DataRank Database

Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution is a research paper published in Gastroenterology (2020). On theSindex it has a DataRank of 0. It has been cited 200 times.

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Open Access200 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)Impact (FWCI 13.20)OA: hybridTopics (102)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Jun Xu ORCID,Sara Rosenthal ORCID,Ling‐juan Zhang ORCID,Ryan McCubbin,Nairika Meshgin

Live enrichment

PubMed:31982409 PMC:PMC7252905 OpenAlex:https://openalex.org/W3001420005

BLRD VA

Grant: I01 BX002213

NIAAA NIH HHS

Grant: P50 AA011999

NIAAA NIH HHS

Grant: R01 AA028550

NIAID NIH HHS

Grant: R37 AI043477

NIDDK NIH HHS

Grant: R56 DK088837

NIDDK NIH HHS

Grant: R01 DK099205

NIDDK NIH HHS

Grant: R01 DK111866

NIDDK NIH HHS

Grant: F32 DK009920

BLRD VA

Grant: I01 BX003635

NCI NIH HHS

Grant: P30 CA023100

NIAAA NIH HHS

Grant: U01 AA029019

BLRD VA

Grant: I01 BX001991

NIAAA NIH HHS

Grant: U01 AA022614

NIAID NIH HHS

Grant: R01 AI043477

NCI NIH HHS

Grant: R01 CA199376

NIAAA NIH HHS

Grant: U01 AA018663

BLRD VA

Grant: I01 BX003732

NIDDK NIH HHS

Grant: R01 DK101737

National Institutes of Health

Grant: 5R01DK101737-04

The Role of Portal Fibroblasts in Cholestatic Liver Fibrosis

National Institutes of Health

Grant: 3P50AA011999-12S1

Southern California Research Center for ALPD and Cirrhosis

National Institutes of Health

Grant: 5R01DK111866-03

Fibrocytes regulate liver fibrosis

National Institutes of Health

Grant: 5R01DK099205-05

Inactivation of Hepatic Stellate Cells During Reversal of Liver Fibrosis

National Institutes of Health

Grant: 1U01AA022614-01A1

The Role of IL-17 in Alcoholic Liver Disease and Cancer

National Institutes of Health

FWCI

13.20

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1053/j.gastro.2020.01.027

publisherhttps://doi.org/10.1053/j.gastro.2020.01.027

publisherhttps://api.elsevier.com/content/article/PII:S0016508520301177?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0016508520301177?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/31982409

Fields of Study

Liver physiology and pathologyHepatocellular Carcinoma Treatment and PrognosisOrgan Transplantation Techniques and Outcomes0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsCarbon TetrachlorideCell DifferentiationCells, CulturedGene Expression RegulationHumansLiver Cirrhosis, ExperimentalMice, TransgenicPPAR gammaProto-Oncogene Protein c-ets-1GATA6 Transcription FactorMiceHepatic Stellate CellsGene Knockdown TechniquesMyofibroblastsPrimary Cell Culture

Keywords

Hepatic stellate cellTranscription factorIdentification (biology)Hepatic fibrosisFibrosisLineage (genetic)Cell biologyComputational biologyBiologyCancer researchMedicineGeneticsInternal medicineGeneEpigenetic regulationInactivation Of Fibrogenic MyofibroblastsLineage-determining Transcription FactorsResolution Of Liver FibrosisGene Expression Regulation (mesh)Liver CirrhosisLiver Cirrhosis, ExperimentalTransgenicMiceGATA6 Transcription Factor1103 Clinical Sciences (for)2.1 Biological and endogenous factorsAnimals (mesh)32 Biomedical and Clinical Sciences (for-2020)Liver Disease (rcdc)Myofibroblasts (mesh)MyofibroblastsCarbon TetrachlorideCells, CulturedHumans (mesh)Nutrition and DieteticsCulturedLiver DiseaseMice (mesh)Proto-Oncogene Protein c-ets-1 (mesh)Experimental (mesh)Cell DifferentiationCarbon Tetrachloride (mesh)Gene Knockdown TechniquesGATA6 Transcription Factor (mesh)Hepatic Stellate Cells (mesh)Cultured (mesh)Digestive Diseases (rcdc)1.1 Normal biological development and functioningCellsClinical SciencesChronic Liver Disease and CirrhosisPrimary Cell CultureTransgenic (mesh)610Cell Differentiation (mesh)Primary Cell Culture (mesh)Mice, Transgenic1114 Paediatrics and Reproductive Medicine (for)Chronic Liver Disease and Cirrhosis (rcdc)Paediatrics and Reproductive Medicine3210 Nutrition and dietetics (for-2020)Proto-Oncogene Protein c-ets-1ExperimentalHepatic Stellate CellsAnimalsHumans3202 Clinical Sciences (for-2020)1.1 Normal biological development and functioning (hrcs-rac)Biomedical and Clinical SciencesGastroenterology & HepatologyPPAR gamma (mesh)Genetics (rcdc)Neurosciences5002.1 Biological and endogenous factors (hrcs-rac)1109 Neurosciences (for)PPAR gammaGene Expression RegulationGastroenterology & Hepatology (science-metrix)Digestive DiseasesGene Knockdown Techniques (mesh)

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being