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Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice

Gastroenterology(2020)10.1053/j.gastro.2020.11.044Source: DataRank Database

Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice is a research paper published in Gastroenterology (2020). On theSindex it has a DataRank of 0. It has been cited 92 times.

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Enrichment:Funding (11 grants)OA: greenTopics (73)Linked Datasets (6)DataCite Reuse (6)IDs (PubMed, PMC)Annotations (2)SDGs (1)

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Authors (19)

Sivanesan Dakshanamurthy ORCID,Matthew McCoy ORCID,Anastasia Mavropoulos,Bedilu Allo ORCID,Aimy Sebastian ORCID

Live enrichment

PubMed:33307028 PMC:PMC7956114

National Institutes of Health

Grant: P30 CA051008

National Institutes of Health

Grant: Cd247

National Institutes of Health

Grant: R01 CA170653

Lawrence Livermore National Laboratory

Grant: LDRD-19-SI-003

Lawrence Livermore National Laboratory

Grant: DE-AC52-07NA27344

AstraZeneca

Grant: 17-40-12-PERA

National Institutes of Health

Grant: 3P30CA051008-16S1

CANCER CENTER SUPPORT GRANT

National Institutes of Health

Grant: 5R01CA170653-03

Cadherin11 in cancer & rheumatoid arthritis: Common target, common therapies? (5)

American Association for Cancer Research

U.S. Department of Energy

American Cancer Society

greenLicense: Elsevier TDM

repositoryhttps://www.osti.gov/servlets/purl/1814101

publisherhttps://api.elsevier.com/content/article/PII:S001650852035513X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S001650852035513X?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7956114

repositoryhttps://www.osti.gov/biblio/1814101

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

PancreasExtracellular MatrixAnimalsMice, KnockoutHumansMiceCarcinoma, Pancreatic DuctalPancreatic NeoplasmsDisease Models, AnimalDisease ProgressionCadherinsDeoxycytidinePancreaticoduodenectomyTumor EscapeGene Expression Regulation, NeoplasticDrug Resistance, NeoplasmFemaleTumor MicroenvironmentCancer-Associated FibroblastsMetallothionein 3Gemcitabine

Keywords

ImmunomodulationInflammationAnti-tumor immunityDesmoplasiaActivated StromaDrug ResistanceClinical sciencesDeoxycytidineMiceCancer-Associated FibroblastsTumor Microenvironment2.1 Biological and endogenous factorsAetiologyCancerMice, KnockoutCadherinsExtracellular MatrixGene Expression Regulation, NeoplasticPancreatic DuctalDisease ProgressionFemaleCarcinoma, Pancreatic DuctalKnockoutOncology and CarcinogenesisImmunologyPancreaticoduodenectomyPaediatrics and Reproductive MedicinePancreatic CancerRare DiseasesAnimalsHumansPancreasNeoplasticBiomedical and Clinical SciencesGastroenterology & HepatologyAnimalCarcinomaNeurosciencesGemcitabineMetallothionein 3Nutrition and dieteticsPancreatic NeoplasmsDisease Models, AnimalGene Expression RegulationDrug Resistance, NeoplasmDisease ModelsNeoplasmTumor EscapeDigestive Diseases

Sustainable Development Goals

SDG 3: 3. Good health

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10.6084/m9.figshare.25583928.v1figshare

Additional file 1 of VDR promotes pancreatic cancer progression in vivo by activating CCL20-mediated M2 polarization of tumor associated macrophage

10.6084/m9.figshare.25583928figshare

Additional file 2 of VDR promotes pancreatic cancer progression in vivo by activating CCL20-mediated M2 polarization of tumor associated macrophage

10.6084/m9.figshare.25584024.v1figshare

Additional file 2 of VDR promotes pancreatic cancer progression in vivo by activating CCL20-mediated M2 polarization of tumor associated macrophage

10.6084/m9.figshare.25584024figshare

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Additional file 1 of Injectable hybrid hydrogels enable enhanced combination chemotherapy and roused anti-tumor immunity in the synergistic treatment of pancreatic ductal adenocarcinoma

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