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Adipose Tissue Macrophages in Metabolic Dysfunction–Associated Steatohepatitis Secrete Extracellular Vesicles That Activate Liver Fibrosis in Obese Male Mice

Gastroenterology(2025)10.1053/j.gastro.2025.03.033Source: DataRank Database

Adipose Tissue Macrophages in Metabolic Dysfunction–Associated Steatohepatitis Secrete Extracellular Vesicles That Activate Liver Fibrosis in Obese Male Mice is a research paper published in Gastroenterology (2025). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (34 grants)Impact (FWCI 9.53)OA: greenTopics (75)IDs (PubMed, PMC, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Felipe C.G. Reis ORCID,Karina Cunha e Rocha,Roi Isaac,Sean Strayer,Cairo Murphy

Live enrichment

PubMed:40204101 PMC:PMC13197014 OpenAlex:https://openalex.org/W4409300459

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Grant: P2BSP3_200177

National Institute of Neurological Disorders and Stroke

Grant: P30 NS047101

Foundation for the National Institutes of Health

Grant: R01DK101395

Janssen Pharmaceuticals Inc

Grant: P50AA011999

Janssen Pharmaceuticals Inc

Grant: 20170515

National Institute on Alcohol Abuse and Alcoholism

Grant: AA011999

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: P30DK063491

National Institutes of Health

Grant: R21HD107516

National Institutes of Health

Grant: AA028550

National Institutes of Health

Grant: AA029019

National Institutes of Health

Grant: DK091183

National Institutes of Health

Grant: DK099205

National Institutes of Health

Grant: DK120515

National Institutes of Health

Grant: DK101737

National Institutes of Health

Grant: R01DK133930

National Institutes of Health

Grant: R01DK137061

National Institutes of Health

Grant: R00DK115998

National Institutes of Health

Grant: R01DK125560

Office of Behavioral and Social Sciences Research

Grant: U24DK132746-01

Larry L Hillblom Foundation

Grant: 2023-D-012-FEL

Larry L Hillblom Foundation

Grant: 2023-D-011-FEL

NIAAA NIH HHS

Grant: R01 AA028550

Swiss National Science Foundation

Grant: 200177

Islet Macrophage Subsets in Metabolic Disease

NIDDK NIH HHS

Grant: R01 DK099205

NIAAA NIH HHS

Grant: U01 AA029019

NIDDK NIH HHS

Grant: P30 DK120515

NIDDK NIH HHS

Grant: R01 DK091183

NIDDK NIH HHS

Grant: R01 DK101737

NIAAA NIH HHS

Grant: U01 AA022614

UCLA Health

Office of Disease Prevention

Office of Naval Research

Office of Nutrition Research

University of California, Los Angeles

FWCI

9.53

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13197014/

publisherhttps://api.elsevier.com/content/article/PII:S0016508525006043?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0016508525006043?httpAccept=text/plain

journalhttps://doi.org/10.1053/j.gastro.2025.03.033

Fields of Study

Extracellular vesicles in diseaseLiver Disease Diagnosis and TreatmentCardiovascular Disease and Adiposity0303 health sciences03 medical and health sciencesAnimalsMaleExtracellular VesiclesMicroRNAsMacrophagesHepatic Stellate CellsObesityMiceAdipose TissueLiver CirrhosisNon-alcoholic Fatty Liver DiseaseMice, Inbred C57BLRibonuclease IIIDisease Models, AnimalLiverDEAD-box RNA HelicasesCells, Cultured

MeSH Terms

Extracellular VesiclesAdipose TissueAnimalsCells, CulturedDisease Models, AnimalLiverLiver CirrhosisMacrophagesMaleMice, Inbred C57BLObesityMicroRNAsRibonuclease IIIMiceDEAD-box RNA HelicasesHepatic Stellate CellsNon-alcoholic Fatty Liver Disease

Keywords

Adipose tissueSecretionExtracellular vesiclesFibrosisVesicleLiver fibrosisEndocrinologyInternal medicineExtracellularLiver tissueAdipose tissue macrophagesChemistryCell biologyMedicineWhite adipose tissueBiologyBiochemistryMicroRNAExosomesMashLipid-associated MacrophagesMaleLiver CirrhosisRibonuclease IIIMacrophagesMice, Inbred C57BLDEAD-box RNA HelicasesMicroRNAsMiceDisease Models, AnimalLiverNon-alcoholic Fatty Liver DiseaseHepatic Stellate CellsAnimalsObesityCells, Cultured

Sustainable Development Goals

SDG 0: Zero hunger