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Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1915829117Source: DataRank Database

Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles is a research paper published in Proceedings of the National Academy of Sciences (2020). On theSindex it has a DataRank of 0. It has been cited 203 times.

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0DataRank · unranked

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Open Access203 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: bronzeTopics (36)IDs (PubMed, PMC)Annotations (2)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

William J. Eagen,Jean C. Lee ORCID,Xiaogang Wang ORCID

Live enrichment

PubMed:31988111 PMC:PMC7022218

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R21AI135613

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01AI141885

BWH | Brigham Research Institute

Grant: Pilot Funding Award

National Institutes of Health

Grant: 5R21AI135613-02

Development of a vesicle-based vaccine platform against Staphylococcus aureus

National Institutes of Health

Grant: 5R01AI141885-03

Staphylococcus aureus extracellular vesicles: host-pathogen interactions

bronzeLicense: https://www.pnas.org/site/aboutpnas/licenses.xhtml

publisherhttps://www.pnas.org/content/pnas/117/6/3174.full.pdf

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.1915829117

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.1915829117

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7022218

https://doi.org/10.1073/pnas.1915829117

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cells, CulturedMacrophagesAnimalsHumansMiceStaphylococcus aureusStaphylococcal InfectionsLipoproteinsSignal TransductionEndocytosisMembrane FluidityPore Forming Cytotoxic ProteinsHost-Pathogen InteractionsInflammasomesExtracellular VesiclesNLR Family, Pyrin Domain-Containing 3 Protein

Keywords

Staphylococcus aureusLipoproteinsExtracellular VesiclesInflammasomesPore-forming ToxinsPore Forming Cytotoxic ProteinsMembrane FluidityMacrophagesStaphylococcal InfectionsEndocytosisMiceHost-Pathogen InteractionsNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsHumansCells, CulturedSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 6: 6. Clean water