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Quantifying the contribution of Fc-mediated effector functions to the antiviral activity of anti–HIV-1 IgG1 antibodies in vivo

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2008190117Source: DataRank Database

Quantifying the contribution of Fc-mediated effector functions to the antiviral activity of anti–HIV-1 IgG1 antibodies in vivo is a research paper published in Proceedings of the National Academy of Sciences (2020). On theSindex it has a DataRank of 0. It has been cited 73 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access73 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)Impact (FWCI 5.39)OA: greenTopics (46)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Mili R. Gajjar,Jian Yu ORCID,Neal N. Padte,Agegnehu Gettie,James Blanchard ORCID

Live enrichment

PubMed:32665438 PMC:PMC7395461 OpenAlex:https://openalex.org/W3042822293

HHS | National Institutes of Health

Grant: RO1-AI145645

HHS | National Institutes of Health

Grant: RO1-AI129802

HHS | National Institutes of Health

Grant: DP1-DA0333263

HHS | National Institutes of Health

Grant: RO1-AI028433

HHS | National Institutes of Health

Grant: RO1-OD011095

HHS | National Institutes of Health

Grant: PO1-AI131365

Bill and Melinda Gates Foundation

Grant: OPP1169162

Bill and Melinda Gates Foundation

Grant: OPP1040731

US Department of Energy contract

Grant: 89233218CNA000001

NIAID NIH HHS

Grant: R01 AI129802

NIAID NIH HHS

Grant: R01 AI028433

NIAID NIH HHS

Grant: R01 AI145645

NIH HHS

Grant: P51 OD011104

NIH HHS

Grant: R01 OD011095

NIAID NIH HHS

Grant: P01 AI131365

NIAID NIH HHS

Grant: R01 AI134328

National Institutes of Health

Grant: 5R01AI134328-02

Bispecific-Antibody-Drug Conjugates for Selective Targeting and Activation of the HIV Latent Reservoir

National Institutes of Health

Grant: 5R01AI129802-06

Bispecific and Trispecific Anti-Env Antibodies for Eliminating HIV Reservoir Cells

National Institutes of Health

Grant: 4R01AI145645-06

Quantifying Effector Functions of Anti-HIV IgG1 Antibodies In Vivo.

National Institutes of Health

Grant: 5P01AI131365-02

Viral dynamics of rebound and control following early treatment of HIV/SIV

National Institutes of Health

Grant: 5R01OD011095-28

Modeling Viral and T Lymphocyte Dynamics

National Institutes of Health

Grant: 5R37AI028433-13

Immune System Modeling/HIV

FWCI

5.39

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

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2025

2026

greenLicense: CC BY NC ND

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7395461

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7395461

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2008190117

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2008190117

journalhttps://doi.org/10.1073/pnas.2008190117

Fields of Study

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and Interaction0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsDisease Models, AnimalHumansImmunoglobulin GMice, TransgenicNeutralization TestsHIV AntibodiesHIV-1HIV InfectionsReceptors, IgGMiceHost-Pathogen InteractionsAntibodies, Neutralizing

Keywords

Monoclonal antibodyEffectorVirologyIn vivoAntibodyVirusInfectivityAntibody-dependent cell-mediated cytotoxicityBiologyImmunologyNeutralizationEffector FunctionsIn Vivo QuantificationHiv-1 DynamicsReceptors, IgGHIV InfectionsMice, TransgenicBiological SciencesHIV AntibodiesAntibodies, NeutralizingDisease Models, AnimalMiceNeutralization TestsImmunoglobulin GHost-Pathogen InteractionsHIV-1AnimalsHumans

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being