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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2025840118Source: DataRank Database

Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0.694. It has been cited 101 times.

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0.694DataRank · unranked

Scored on demand from live citation data

Open Access101 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)Impact (FWCI 5.43)OA: hybridTopics (115)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)SDGs (2)

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Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.694

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (33)

Ingmar N. Bastian ORCID,Mark D. Long ORCID,Michelle T. Dow,Weihua Li ORCID,Tao Liu ORCID

Live enrichment

PubMed:33602823 PMC:PMC7923353 OpenAlex:https://openalex.org/W3131620481

NIH HHS

Grant: DP5 OD017937

NIAAA NIH HHS

Grant: U01 AA027681

NCI NIH HHS

Grant: U24 CA232979

NCI NIH HHS

Grant: P01 CA128814

NIAID NIH HHS

Grant: R01 AI043477

NCI NIH HHS

Grant: R01 CA211794

NLM NIH HHS

Grant: T15 LM011271

NIGMS NIH HHS

Grant: P41 GM103412

NIH HHS

Grant: S10 OD021784

NIGMS NIH HHS

Grant: R24 GM137200

NIAID NIH HHS

Grant: R37 AI043477

NCATS NIH HHS

Grant: UL1 TR001442

NIAAA NIH HHS

Grant: P50 AA011999

National Institutes of Health

Grant: 5R01AI043477-10

Regulation of NF-kB and IKK by proinflammatory stimuli

National Institutes of Health

Grant: 2T15LM011271-11

San Diego Biomedical Informatics Education & Research (SABER)

National Institutes of Health

Grant: 3R24GM137200-02S1

The National Center for Microscopy and Imaging Research, a Community-wide Scientific Resource

National Institutes of Health

Grant: 5R01CA211794-03

Role of p62/SQSTM1 in obesity-induced liver cancer

National Institutes of Health

Grant: 5DP5OD017937-03

Network approaches to identify cancer drivers from high-dimensional tumor data

National Institutes of Health

Grant: 2UL1TR001442-06

UC San Diego Clinical and Translational Research Institute

National Institutes of Health

Grant: 3U24CA232979-01S1

Immuno-Oncology Translation Network: Data Management and Resource-Sharing Center at RPCI

National Institutes of Health

Grant: 3P50AA011999-12S1

Southern California Research Center for ALPD and Cirrhosis

National Institutes of Health

Grant: 1S10OD021784-01A1

FEI TITAN HALO 300kV INTERMEDIATE VOLTAGE ELECTRON MICROSCOPE

National Institutes of Health

Grant: 5P01CA128814-08

ER Stress and Mitochondrial Biogenesis in Melanoma

National Institutes of Health

Grant: 1U01AA027681-01

Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors

National Institutes of Health

Grant: 5P41GM103412-29

IVEM and Image Analysis Resource

FWCI

5.43

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/full/10.1073/pnas.2025840118

HYBRIDhttps://www.pnas.org/doi/full/10.1073/pnas.2025840118

publisherhttps://www.pnas.org/doi/full/10.1073/pnas.2025840118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2025840118

journalhttps://doi.org/10.1073/pnas.2025840118

Fields of Study

Immunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersHistone Deacetylase Inhibitors ResearchMedicineBiology0301 basic medicine03 medical and health sciencesAnimalsAntigen PresentationAntineoplastic AgentsApoptosisB7-H1 AntigenBiomarkers, TumorCD8-Positive T-LymphocytesCell ProliferationDrug Therapy, CombinationGene Expression Regulation, NeoplasticHistocompatibility Antigens Class IHumansImmune Checkpoint InhibitorsImmunotherapyMiceNF-kappa BNeoplasmsOxaliplatinPrognosisSurvival RateTumor Cells, CulturedXenograft Model Antitumor Assaysp300-CBP Transcription Factors

MeSH Terms

OxaliplatinImmune Checkpoint InhibitorsAnimalsAntineoplastic AgentsDrug Therapy, CombinationHumansImmunotherapyNeoplasmsPrognosisTumor Cells, CulturedBiomarkers, TumorHistocompatibility Antigens Class IGene Expression Regulation, NeoplasticSurvival RateNF-kappa BApoptosisAntigen PresentationCD8-Positive T-LymphocytesXenograft Model Antitumor AssaysCell Proliferationp300-CBP Transcription FactorsMiceB7-H1 Antigen

Keywords

Cross-presentationAntigen presentationMHC class IAntigen processingCytotoxic T cellMajor histocompatibility complexAntigenCell biologyMHC restrictionBiologyT cellAntigen-presenting cellCD8Immune systemImmunologyCancer researchChemistryBiochemistryNF-κBHistone acetylationMhc-iImmune Checkpoint InhibitorsApoptosisCD8-Positive T-LymphocytesB7-H1 AntigenMicename=GeneralNeoplasms/dk/atira/pure/subjectarea/asjc/1000p300-CBP Transcription FactorsNF-kBCancerTumorCulturedNF-kappa BBiological SciencesPrognosisTumor CellsGene Expression Regulation, NeoplasticOxaliplatinSurvival Rate5.1 PharmaceuticalsCombinationDrug Therapy, CombinationImmunotherapy570Oncology and Carcinogenesis610Antineoplastic AgentsDrug TherapyClinical ResearchGeneticsBiomarkers, TumorAnimalsHumansCell ProliferationNeoplasticBiomedical and Clinical SciencesHistocompatibility Antigens Class IXenograft Model Antitumor AssaysGene Expression RegulationBiomarkers

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of BAP1 mutations inhibit the NF-κB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma

10.6084/m9.figshare.24144085.v1figshare

Additional file 1 of BAP1 mutations inhibit the NF-κB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma

10.6084/m9.figshare.24144085figshare