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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2101555118Source: DataRank Database

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 79 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access79 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 4.56)OA: hybridTopics (49)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Jian Zheng ORCID,Krishani Dinali Perera ORCID,Lok-Yin Roy Wong ORCID,David K. Meyerholz ORCID,Harry Nhat Nguyen

Live enrichment

PubMed:34210738 OpenAlex:https://openalex.org/W3173329226

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01 AI109039

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: P01 AI060699

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01 AI129269

FWCI

4.56

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1073/pnas.2101555118

publisherhttps://doi.org/10.1073/pnas.2101555118

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2101555118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2101555118

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34210738

Fields of Study

SARS-CoV-2 and COVID-19 ResearchInhalation and Respiratory Drug Deliverythermodynamics and calorimetric analyses

MeSH Terms

Angiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Coronavirus 3C ProteasesCoronavirus Papain-Like ProteasesCOVID-19 Drug TreatmentAnimalsAntiviral AgentsDeuteriumDisease Models, AnimalDrug Evaluation, PreclinicalFemaleLactamsLeucineLungMice, TransgenicModels, MolecularProtease InhibitorsProtein ConformationPyrrolidinesSulfonic AcidsMolecular StructureCrystallography, X-RayTransgenesMice

Keywords

ProteaseVirologyVero cellVirusViral replicationBiologyProtease inhibitor (pharmacology)EnzymeCoronavirusTiterSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)NidoviralesMicrobiologyPharmacologyCoronavirus disease 2019 (COVID-19)Viral loadMedicineBiochemistryPathologyInfectious disease (medical specialty)Disease

Sustainable Development Goals

SDG 0: Good health and well-being