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STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [ 18 F]FLT PET imaging

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105390118Source: DataRank Database

STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [ 18 F]FLT PET imaging is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 19 times.

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Enrichment:Funding (7 grants)OA: bronzeTopics (75)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Evan R. Abt ORCID,Thuc Le ORCID,Arthur Cho ORCID,Amanda M. Dann ORCID,Jing Cui ORCID

Live enrichment

PubMed:34480004 PMC:PMC8433573

NIH R01

Grant: 1R01CA250529-01A1

Leveraging Vulnerabilities Induced by STING Activation in Pancreatic Cancer

UCLA Tumor Immunology Training Grant

Grant: T32CA009120

NCI NIH HHS

Grant: P30 CA016042

NCI NIH HHS

Grant: R01 CA250529

NCI NIH HHS

Grant: P50 CA211015

NCI NIH HHS

Grant: R01 CA260678

National Institutes of Health

Grant: 5T32CA009120-45

UCLA Tumor Immunology Institutional Traning Grant

bronzeLicense: https://www.pnas.org/site/aboutpnas/licenses.xhtml

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2105390118

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2105390118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2105390118

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8433573

repositoryhttps://ir.ymlib.yonsei.ac.kr/handle/22282913/190516

Fields of Study

0301 basic medicine03 medical and health sciencesAnimalsCell Line, TumorDideoxynucleosidesFemaleFluorine RadioisotopesHumansInterferon Type IMaleMembrane ProteinsMiceMice, Inbred NODPancreatic NeoplasmsPositron-Emission TomographySignal TransductionXenograft Model Antitumor AssaysSTING Protein

MeSH Terms

Cell Line, TumorAnimalsMice, Inbred NODHumansMicePancreatic NeoplasmsFluorine RadioisotopesInterferon Type IMembrane ProteinsDideoxynucleosidesPositron-Emission TomographyXenograft Model Antitumor AssaysSignal TransductionFemaleMaleSTING Protein

Keywords

InterferonPancreatic cancerPET imagingNucleotide MetabolismStingMale570Fluorine RadioisotopesInterferon Type I / metabolism*Oncology and CarcinogenesisImmunology610Dideoxynucleosides / administration & dosage*Fluorine Radioisotopes / administration & dosage*Positron-Emission Tomography / methods*Cell LineMiceRare DiseasesSTING ProteinPancreatic Neoplasms / metabolism*Pancreatic Neoplasms / pathologyMice, Inbred NODCell Line, TumorGeneticsMembrane Proteins / metabolism*AnimalsHumansCancerTumorBiomedical and Clinical SciencesMembrane ProteinsXenograft Model Antitumor AssaysDideoxynucleosidesPancreatic NeoplasmsPositron-Emission TomographyInterferon Type IBiomedical ImagingInbred NODFemaleDigestive DiseasesSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health

STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [ 18 F]FLT PET imaging

FAIR Checklist

Authors (17)

Funding (7 grants)

Open Access

Topics

Annotations (Europe PMC)