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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2108079118Source: DataRank Database

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0.598. It has been cited 53 times.

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0.598DataRank · unranked

Scored on demand from live citation data

Open Access53 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 3.84)OA: hybridTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.598

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (29)

Anders B. Klein ORCID,Ethan D. McSpadden ORCID,Nane Griem‐Krey ORCID,Sara M. Ø. Solbak ORCID,Josh Houlton ORCID

Live enrichment

PubMed:34330837 PMC:PMC8346900 OpenAlex:https://openalex.org/W3184126906

Lundbeckfonden

Grant: R83-2011-8000

Lundbeckfonden

Grant: R77-2011-A6415

Lundbeckfonden

Grant: R139-2012-12270

Lundbeckfonden

Grant: R190-2014-3710

Lundbeckfonden

Grant: R192-2015-666

Lundbeckfonden

Grant: R303-2018-3162

Lundbeckfonden

Grant: R277-2018-260

Novo Nordisk

Grant: NNF17OC0028664

Novo Nordisk

Grant: NNF14CC0001

Novo Nordisk

Grant: NNF19SA0057841

Det Frie Forskningsråd

Grant: 8020-00156B

Det Frie Forskningsråd

Grant: 1333-00161B

ZonMw

Grant: NWO-VIDI 016.Vidi.188.014

Dutch Research Council (NWO)

Grant: 016.Vidi.188.014

NIGMS NIH HHS

Grant: P30 GM124169

NIGMS NIH HHS

Grant: R01 GM124149

Novo Nordisk Foundation Center for Protein Research

Grant: PI Jesper Velgaard Olsen

National Institutes of Health

Grant: 2R01GM124149-06

Eliminating Critical Systematic Errors In Structural Biology With Next-Generation Simulation

Independent Research Fund Denmark

Grant: unidentified

unidentified

National Institutes of Health

Grant: 2P30GM124169-06

ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE)

FWCI

3.84

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/content/pnas/118/31/e2108079118.full.pdf

publisherhttps://www.pnas.org/content/pnas/118/31/e2108079118.full.pdf

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2108079118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2108079118

journalhttps://doi.org/10.1073/pnas.2108079118

Fields of Study

Neuroscience and Neuropharmacology ResearchBlood disorders and treatmentsMitochondrial Function and Pathology0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

NeuroprotectionProtein DomainsBinding SitesCarboxylic AcidsCyclopentanesHumansProtein BindingSodium OxybateSignal TransductionGene Expression Regulation, EnzymologicCrystallography, X-RayCalcium-Calmodulin-Dependent Protein Kinase Type 2HEK293 Cells

Keywords

NeuroprotectionNeuroscienceDomain (mathematical analysis)ChemistryPharmacologyPsychologyBiologyMathematicsExcitotoxicityX-ray crystallographyPhotoaffinity LabelingHocpcaPhotothrombotic StrokeEnzymologic570photothrombotic storke1.1 Normal biological development and functioningCarboxylic AcidsCyclopentanesCrystallography, X-RayGene Expression Regulation, EnzymologicMedicinal and Biomolecular ChemistryProtein DomainsHumansCrystallographyBinding SitesNeurosciencesBiological SciencesBrain DisordersHEK293 CellsGene Expression Regulation5.1 PharmaceuticalsChemical SciencesNeurologicalX-RayCalcium-Calmodulin-Dependent Protein Kinase Type 2Sodium OxybateProtein BindingSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being