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Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2108484118Source: DataRank Database

Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 37 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access37 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)OA: hybridTopics (56)IDs (PubMed, PMC)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Rafael Shimkunas,Zhong Jian ORCID,Leighton T. Izu ORCID,Donald M. Bers ORCID,Ye Chen‐Izu ORCID

Live enrichment

PubMed:34326268 PMC:PMC8346795

HHS | National Institutes of Health

Grant: R01-HL123526

HHS | National Institutes of Health

Grant: R01-HL141460

HHS | National Institutes of Health

Grant: R01-HL149431

HHS | National Institutes of Health

Grant: R01-HL030077

HHS | National Institutes of Health

Grant: P01-HL141084

HHS | National Institutes of Health

Grant: R01-HL142282

HHS | National Institutes of Health

Grant: F31-HL129746

American Heart Association

Grant: 14GRNT20510041

NHLBI NIH HHS

Grant: R01 HL030077

NHLBI NIH HHS

Grant: R01 HL142282

NHLBI NIH HHS

Grant: P01 HL141084

NHLBI NIH HHS

Grant: R01 HL141460

NHLBI NIH HHS

Grant: R01 HL149431

NHLBI NIH HHS

Grant: R01 HL123526

NHLBI NIH HHS

Grant: F31 HL129746

NHLBI NIH HHS

Grant: R01 HL159993

NHLBI NIH HHS

Grant: R35 HL166575

National Institutes of Health

Grant: 5P01HL141084-04

Elucidating Electro-Mechanical Dysfunction in Heart Failure with Human Stem Cell Models

National Institutes of Health

Grant: 5R01HL142282-03

CaMKII activation and regulation in adult cardiac myocytes

National Institutes of Health

Grant: 5R01HL149431-03

The Functional Connectome of the Mechanically Loaded Cardiomyocyte

National Institutes of Health

Grant: 5R01HL030077-06

ION CONTROL OF CARDIAC MUSCLE CONTRACTION: E-C COUPLING

National Institutes of Health

Grant: 5R01HL141460-02

MECHANICAL LOAD EFFECT ON CARDIAC EXCITATION-CONTRACTION COUPLING

National Institutes of Health

Grant: 1F31HL129746-01A1

Mechano-chemo transduction in the single rabbit cardiomyocyte contracting in cross-linked 3D viscoelastic gel

National Institutes of Health

Grant: 5R01HL123526-02

Novel Cell-in-Gel System for Mechanotransduction Study at the Single Cell Level

hybridLicense: cc-by-nc-nd

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2108484118

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2108484118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2108484118

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8346795

Unpaywallhttps://escholarship.org/uc/item/5fr4f7c2

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Cells, CulturedMyocytes, CardiacAnimalsRabbitsCalciumHydrogelsPatch-Clamp TechniquesSignal TransductionCalcium SignalingAction PotentialsMyocardial ContractionMaleNitric Oxide Synthase Type IArrhythmias, CardiacViscoelastic SubstancesElectrophysiological PhenomenaBiomechanical Phenomena

Keywords

Action potentialCardiac ArrhythmiaMechanosensitive Ion ChannelsMechano-chemo-transductionIntracellular Calcium CyclingMalePatch-Clamp TechniquesCellsMedical PhysiologyBiomedical Engineering610Action PotentialsNitric Oxide Synthase Type IViscoelastic SubstancesArrhythmiasCardiovascularEngineering616AnimalsMyocytes, CardiacCalcium SignalingCells, CulturedMyocytesCulturedBiomedical and Clinical SciencesArrhythmias, CardiacHydrogelsBiological SciencesMyocardial ContractionBiomechanical PhenomenaElectrophysiological PhenomenaHeart DiseaseCalciumRabbitsCardiacSignal Transduction