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Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2117065119Source: DataRank Database

Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis is a research paper published in Proceedings of the National Academy of Sciences (2022). On theSindex it has a DataRank of 0. It has been cited 75 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)OA: greenTopics (81)IDs (PubMed, PMC)SDGs (1)

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Authors (20)

Jayanth S. Shankara Narayanan ORCID,Jacob R. Andrew,Marjaana Ojalill ORCID,A. Barrie,Shulin Jiang ORCID

Live enrichment

PubMed:35467979 PMC:PMC9169934

DOD | United States Army | MEDCOM | Congressionally Directed Medical Research Programs

Grant: W81XWH19101

HHS | NIH | National Cancer Institute

Grant: R01CA24756

HHS | NIH | National Cancer Institute

Grant: R01CA254342

Ovarian Cancer Research Fund

Grant: OCRA 650255

HHS | NIH | National Cancer Institute

Grant: T32-CA121938

NCI NIH HHS

Grant: T32 CA121938

NIAID NIH HHS

Grant: P01 AI039671

NCI NIH HHS

Grant: P30 CA023100

NCI NIH HHS

Grant: R01 CA247562

NIH HHS

Grant: S10 OD021831

National Institutes of Health

Grant: 5P01AI039671-21

Costimulatory Mechanisms of Autoimmunity

National Institutes of Health

Grant: 1S10OD021831-01A1

Super-resolution confocal microscope

National Institutes of Health

Grant: 5T32CA121938-14

UCSD Cancer Center Training Program in Drug Development

National Institutes of Health

Grant: 5R01ES024756-06

Mechanism of manganese-induced impairment of astrocytic glutamate transporters

National Institutes of Health

Grant: 1R01CA254342-01

Reprogramming the Tumor Microenvironment in Ovarian Cancer

National Institutes of Health

Grant: 3P30CA023100-25S4

Specialized Cancer Center Support Grant

greenLicense: cc-by-nc-nd

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9169934

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2117065119

repositoryhttps://escholarship.org/uc/item/1dj7j519

Europe_PMChttps://europepmc.org/articles/PMC9169934

Europe_PMChttps://europepmc.org/articles/PMC9169934?pdf=render

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceOvarian NeoplasmsReceptors, ImmunologicLigandsFemaleFocal Adhesion Protein-Tyrosine KinasesFocal Adhesion Kinase 1Carcinoma, Ovarian EpithelialImmunosuppression Therapy

Keywords

ImmunotherapyFAKHigh-grade Serous Ovarian CancerTertiary Lymphoid StructuresCd155Women's Health (rcdc)Ligands (mesh)Carcinoma, Ovarian EpithelialLigandsClinical Research (rcdc)MiceImmunologicOvarian EpithelialReceptors2.1 Biological and endogenous factorsAnimals (mesh)Receptors, Immunologic32 Biomedical and Clinical Sciences (for-2020)CancerCancer (rcdc)Ovarian NeoplasmsHumans (mesh)3 Good Health and Well Being (sdg)Mice (mesh)Biological SciencesFocal Adhesion Kinase 1 (mesh)Ovarian Cancer5.1 PharmaceuticalsFemaleBiotechnologyImmunologic (mesh)Oncology and CarcinogenesisImmunology610Focal Adhesion Protein-Tyrosine Kinases (mesh)Ovarian Neoplasms (mesh)Ovarian Epithelial (mesh)Biotechnology (rcdc)Rare Diseases (rcdc)Rare DiseasesCancer GenomicsOvarian Cancer (rcdc)Clinical Research5.1 Pharmaceuticals (hrcs-rac)GeneticsAnimalsHumans3204 Immunology (for-2020)Immunosuppression TherapyBiomedical and Clinical SciencesGenetics (rcdc)Human GenomeCarcinomaImmunotherapy (rcdc)2.1 Biological and endogenous factors (hrcs-rac)Cancer (hrcs-hc)Immunosuppression Therapy (mesh)Human Genome (rcdc)Orphan DrugGood Health and Well Being3211 Oncology and Carcinogenesis (for-2020)Female (mesh)Focal Adhesion Kinase 1Focal Adhesion Protein-Tyrosine KinasesOrphan Drug (rcdc)Women's HealthCancer Genomics (rcdc)

Sustainable Development Goals

SDG 3: 3. Good health