Cell size and polarization determine cytokinesis furrow ingression dynamics in mouse embryos is a research paper published in Proceedings of the National Academy of Sciences (2022). On theSindex it has a DataRank of 0.733. It has been cited 20 times, with 18 citing works in its 1-hop citation network.
Significance The final step of cell division, termed cytokinesis, comprises the constriction of a furrow that divides the cytoplasm to form two daughter cells. Although cytokinesis is well studied in traditional cell systems, how cytokinesis is regulated in complex multicellular settings and during cell-fate decisions is less well understood. Here, using live imaging and physical and molecular interventions, we find that the emergence of cell polarity during mouse embryo morphogenesis dramatically impacts cytokinesis mechanisms. Specifically, the assembly of the apical domain in outer cells locally inhibits the cytokinetic machinery, leading to an unexpected laterally biased cytokinesis.
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Base Score Contribution
0.457
From this paper's citation signal
Citation Network Contribution
0.276
From 13 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 62% comes from its base citations and 38% from the citation network (13 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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