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The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2202815120Source: DataRank Database

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores is a research paper published in Proceedings of the National Academy of Sciences (2023). On theSindex it has a DataRank of 0. It has been cited 46 times.

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Open Access46 citations

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Enrichment:Funding (20 grants)Impact (FWCI 5.70)OA: greenTopics (50)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)SDGs (1)

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Findable (2/2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (23)

Sushila Kumari ORCID,Chaoyi Xu ORCID,Sooin Jang ORCID,Jiong Shi ORCID,Ryan C. Burdick ORCID

Live enrichment

PubMed:36943880 PMC:PMC10068764 OpenAlex:https://openalex.org/W4328048812

NIH HHS

Grant: P30GM110758

NIAID NIH HHS

Grant: R01 AI052014

NIH HHS

Grant: R01GM105672

NIH HHS

Grant: R21GM109466

NIGMS NIH HHS

Grant: T32 GM008283

NIH HHS

Grant: R01AI162260

Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research

Grant: Intramural AIDS Targeted Antiviral Program grant funding

Singapore Agency for Science

Grant: Technology and Research Graduate Scholarship

NIAID NIH HHS

Grant: P50 AI150481

NIAID NIH HHS

Grant: U54 AI170791

NIGMS NIH HHS

Grant: R01 GM116961

Pittsburgh Center for HIV Protein Interactions

Grant: Collaboration Development Pilot Program awards

National Institutes of Health

Grant: 5R01GM116961-04

Breakthrough Molecular Dynamics Research via an Anton2 Supercomputer

National Institutes of Health

Grant: 1U54AI170791-01

Pittsburgh Center for HIV Protein Interactions (PCHPI)

National Institutes of Health

Grant: 5R01GM105672-13

The mechanism of ESCRT-mediated surveillance of the nuclear envelope barrier

National Institutes of Health

Grant: 5P30GM110758-04

Molecular Design of Advanced Biomaterials

National Institutes of Health

Grant: 5R01AI052014-03

Nuclear Localization of HIV-1 Preintegration Complexes

National Institutes of Health

Grant: 3P50AI150481-13S1

MicroCal PEAQ-DSC

National Institutes of Health

Grant: 5R01AI162260-02

A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid

National Institutes of Health

Grant: 1R21GM109466-01

Generating nuclear pore complex mimics with DNA origami

FWCI

5.70

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

greenLicense: cc-by-nc-nd

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10068764/pdf/pnas.202202815.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10068764

journalhttps://doi.org/10.1073/pnas.2202815120

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36943880

Fields of Study

HIV Research and TreatmentNuclear Structure and FunctionHIV/AIDS drug development and treatment0301 basic medicine03 medical and health sciencesHumansCapsid ProteinsCapsidHIV-1Active Transport, Cell NucleusNuclear Pore Complex ProteinsHIV SeropositivityHIV InfectionsNuclear Pore

MeSH Terms

CapsidHIV SeropositivityHumansHIV-1HIV InfectionsActive Transport, Cell NucleusNuclear PoreNuclear Pore Complex ProteinsCapsid Proteins

Keywords

CapsidNucleoporinNuclear poreRandom hexamerNuclear transportCell biologyBiophysicsNucleusChemistryBiologyCrystallographyVirologyCell nucleusVirusNup153Nuclear EntryHiv-1 CapsidLattice StabilizationRrr-motifNuclear Pore Complex ProteinsHIV SeropositivityHIV-1Active Transport, Cell NucleusHumansCapsid ProteinsHIV InfectionsBiological Sciences

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of HIV-1 with gag processing defects activates cGAS sensing

10.6084/m9.figshare.25884984.v1figshare

Additional file 1 of HIV-1 with gag processing defects activates cGAS sensing

10.6084/m9.figshare.25884984figshare