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Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca 2+ channel Ca V 1.2

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221242120Source: DataRank Database

Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca 2+ channel Ca V 1.2 is a research paper published in Proceedings of the National Academy of Sciences (2023). On theSindex it has a DataRank of 0. It has been cited 14 times.

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Open Access14 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (17 grants)Impact (FWCI 2.43)OA: greenTopics (65)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Silvia G. del Villar ORCID,Maartje Westhoff ORCID,Alexandre Costa ORCID,Andrea M. Coleman ORCID,Johannes Hell ORCID

Live enrichment

PubMed:36976770 PMC:PMC10083594 OpenAlex:https://openalex.org/W4361218625

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: R01HL159304

HHS | NIH | National Institute on Aging

Grant: R01AG063796

HHS | NIH | National Institute of General Medical Sciences

Grant: R01GM127513

HHS | NIH | National Institute of General Medical Sciences

Grant: T32GM099608

American Heart Association

Grant: 827909

HHS | NIH | National Institute of General Medical Sciences

Grant: R25GM056765

HHS | NIH | National Institute of General Medical Sciences

Grant: T32GM113770

HHS | NIH | National Institute of Neurological Disorders and Stroke

Grant: R01NS123050

HHS | NIH | National Institute on Aging

Grant: RF1AG055357

National Institutes of Health

Grant: 5R01NS123050-03

Postsynaptic Signaling by Norepinephrine and cAMP

National Institutes of Health

Grant: 1R01GM127513-01A1

Membrane contact sites regulate cellular excitability

National Institutes of Health

Grant: 5T32GM099608-04

Pharmacology Training: Bench to Bedside

National Institutes of Health

Grant: 2RF1AG055357-06A1

Dysregulation of Cav1.2 by beta amyloid peptide

National Institutes of Health

Grant: 5T32GM113770-05

UC Davis Training Program in Chemical Biology

National Institutes of Health

Grant: 5R25GM056765-10

UC Davis Biology Program

National Institutes of Health

Grant: 5R01HL159304-02

Lipid regulation of Cardiac Excitation-Contraction coupling

National Institutes of Health

Grant: 5R01AG063796-02

Molecular choreography of CaV1.2 channels in the aging myocardium

FWCI

2.43

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: cc-by-nc-nd

repositoryhttps://escholarship.org/content/qt9cz4g77z/qt9cz4g77z.pdf

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2221242120

repositoryhttps://escholarship.org/uc/item/9cz4g77z

journalhttps://doi.org/10.1073/pnas.2221242120

Fields of Study

Cardiac electrophysiology and arrhythmiasIon channel regulation and functionReceptor Mechanisms and Signaling03 medical and health sciences0303 health sciencesCells, CulturedAngiotensin IIExcitation Contraction CouplingSignal TransductionMyocytes, CardiacCalcium Channels, L-TypePhosphatidylinositol 4,5-Diphosphate

MeSH Terms

Angiotensin IICells, CulturedSignal TransductionPhosphatidylinositol 4,5-DiphosphateCalcium Channels, L-TypeMyocytes, CardiacExcitation Contraction Coupling

Keywords

Angiotensin IICav1.2ChemistryEndocrinologyInternal medicineAngiotensin II receptor type 1SarcolemmaRenin–angiotensin systemBiophysicsAngiotensin receptorMyocyteCell biologyReceptorVoltage-dependent calcium channelBiologyBiochemistryCalciumMedicineL-type calcium channelsPip2Ec-couplingIon Channel TraffickingPhosphatidylinositol 4,5-DiphosphateCalcium Channels, L-TypeCellsMedical Physiology610Cardiovascularchannel traffickingMyocytes, CardiacCells, CulturedExcitation Contraction CouplingMyocytesCulturedBiomedical and Clinical Sciences-couplingBiological SciencesL-TypePhosphatidylinositol 4Heart Disease5.1 PharmaceuticalsHypertension5-DiphosphateCalcium ChannelsCardiacSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca 2+ channel Ca V 1.2

FAIR Checklist

Authors (9)

Funding (17 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)