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Cochlear zinc signaling dysregulation is associated with noise-induced hearing loss, and zinc chelation enhances cochlear recovery

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2310561121Source: DataRank Database

Cochlear zinc signaling dysregulation is associated with noise-induced hearing loss, and zinc chelation enhances cochlear recovery is a research paper published in Proceedings of the National Academy of Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 1.79)OA: hybridTopics (48)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Sofie Brutsaert,Christopher L. Cunningham ORCID,Amantha Thathiah ORCID,Thanos Tzounopoulos ORCID,Brandon Bizup ORCID

Live enrichment

PubMed:38354264 PMC:PMC10895357 OpenAlex:https://openalex.org/W4391824330

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Grant: DC019618

HHS | NIH | National Institute of Biomedical Imaging and Bioengineering

Grant: EB033172

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Grant: DC019027

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Grant: DC019195

HHS | NIH | National Institute on Aging

Grant: AG058851

HHS | NIH | National Institute on Deafness and Other Communication Disorders

Grant: DC020923

NIDCD NIH HHS

Grant: R01 DC020923

NIDCD NIH HHS

Grant: R01 DC019618

NIDCD NIH HHS

Grant: R21 DC019195

NIA NIH HHS

Grant: R01 AG058851

NIDCD NIH HHS

Grant: F31 DC019027

NIBIB NIH HHS

Grant: R01 EB033172

National Institutes of Health

Grant: 1R01EB033172-01A1

Fluorescent Indicators for Imaging Synaptic Zinc in Cortical Sound Processing

National Institutes of Health

Grant: 5R01DC020923-03

Cortical neuromodulatory mechanisms underlying adaptation and plasticity

National Institutes of Health

Grant: 5R01DC019618-04

Synaptic, Cellular and Circuit Mechanisms of Cortical Plasticity after Cochlear Damage

National Institutes of Health

Grant: 5R01AG058851-03

Regulation of gamma-secretase function in Alzheimer's disease

National Institutes of Health

Grant: 5F31DC019027-02

The Role of Vesicular Zinc in Noise-induced Cochlear Degeneration and Hearing Loss

National Institutes of Health

Grant: 1R21DC019195-01

Mechanisms of Protein Assembly and Transport in Hair Cells

FWCI

1.79

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2310561121

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2310561121

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2310561121

journalhttps://doi.org/10.1073/pnas.2310561121

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38354264

Fields of Study

Trace Elements in HealthHearing, Cochlea, Tinnitus, GeneticsRNA regulation and disease0301 basic medicine0303 health sciences03 medical and health sciencesMiceAnimalsHearing Loss, Noise-InducedZincCochleaNoiseHearingEvoked Potentials, Auditory, Brain StemAuditory Threshold

MeSH Terms

AnimalsAuditory ThresholdCochleaHearingHearing Loss, Noise-InducedNoiseZincEvoked Potentials, Auditory, Brain StemMice

Keywords

ZincNoise-induced hearing lossHearing lossCell biologyNeurodegenerationSignal transductionChemistryBiologyNeuroscienceMedicineInternal medicineAudiologyNoise exposureCochleaDegenerationRecoveryMiceHearing Loss, Noise-InducedHearingEvoked Potentials, Auditory, Brain StemAnimalsAuditory ThresholdBiological SciencesNoise

Sustainable Development Goals

SDG 0: Good health and well-being