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PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against elevated manganese

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2402538121Source: DataRank Database

PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against elevated manganese is a research paper published in Proceedings of the National Academy of Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 13 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access13 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 2.97)OA: hybridTopics (26)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Thomas Jursa ORCID,Eun Jeong Cho ORCID,Walter Fast ORCID,Kevin N. Dalby ORCID,Donald R. Smith ORCID

Live enrichment

PubMed:38905240 PMC:PMC11214094 OpenAlex:https://openalex.org/W4399907547

HHS | NIH | National Institute of Environmental Health Sciences

Grant: R01-ES024812

HHS | NIH | National Institute of Environmental Health Sciences

Grant: R01-ES031574

Cancer Prevention and Research Institute of Texas

Grant: RP210088

NIEHS NIH HHS

Grant: R01 ES031574

NIEHS NIH HHS

Grant: R01 ES024812

FWCI

2.97

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2402538121

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2402538121

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2402538121

journalhttps://doi.org/10.1073/pnas.2402538121

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38905240

Fields of Study

Trace Elements in HealthIron Metabolism and DisordersCancer, Hypoxia, and Metabolism

MeSH Terms

HomeostasisHumansIronManganeseCation Transport ProteinsHypoxia-Inducible Factor 1, alpha SubunitHEK293 CellsHypoxia-Inducible Factor-Proline Dioxygenases

Keywords

HomeostasisChemistryDownregulation and upregulationManganeseIntracellularEnzymeBiochemistryHydroxylationCell biologyBiophysicsBiologyGenehypoxia-inducible factorSlc30a10Mismetallation

Sustainable Development Goals

SDG 0: Clean water and sanitation

PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against elevated manganese

FAIR Checklist

Authors (7)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)