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APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2408179122Source: DataRank Database

APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 3.14)OA: hybridTopics (38)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Margo Coxon,Bianca Larsen ORCID,Maxwell J. Allison,Ariana Chadha,Isabelle Mittelstadt

Live enrichment

PubMed:39772743 OpenAlex:https://openalex.org/W4406143732

NSF | BIO | Division of Molecular and Cellular Biosciences

Grant: MCB 1817499

HHS | NIH | National Institute of General Medical Sciences

Grant: R35 GM144215

HHS | NIH | National Cancer Institute

Grant: R01CA218112

HHS | NIH | National Cancer Institute

Grant: R01CA269784

National Institutes of Health

Grant: 1R01CA269784-01A1

Regulation of APOBEC3 cytidine deaminase-induced mutation during cancer development

National Science Foundation

Grant: 1817499

The Interplay of Replication and Transcription in Fragility of Structured DNA

National Institutes of Health

Grant: 3R35GM144215-03S1

Replication through DNA Structures and Consequences for Genome Stability

National Institutes of Health

Grant: 3R01CA218112-04S1

Mechanisms of genome instability induced by APOBEC Cytidine Deaminases & its impacts during cancer development - Diversity Supplement

FWCI

3.14

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2408179122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2408179122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2408179122

journalhttps://doi.org/10.1073/pnas.2408179122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39772743

Fields of Study

Genetic Neurodegenerative DiseasesDNA Repair MechanismsMitochondrial Function and Pathology0301 basic medicine03 medical and health sciences

MeSH Terms

R-Loop StructuresAICDA (Activation-Induced Cytidine Deaminase)Cytidine DeaminaseDeaminationDNA DamageHumansProteinsSaccharomyces cerevisiaeMinor Histocompatibility AntigensTrinucleotide Repeat ExpansionGenomic Instability

Keywords

Cytidine deaminaseActivation-induced (cytidine) deaminaseBiologyDNA repairMolecular biologyCytidineDNAGeneticsBiochemistryEnzymeSomatic hypermutationAICDA (Activation-Induced Cytidine Deaminase)ProteinsSaccharomyces cerevisiaeBiological SciencesGenomic InstabilityMinor Histocompatibility AntigensDeaminationHumansR-Loop StructuresTrinucleotide Repeat ExpansionDNA Damage