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Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2409266122Source: DataRank Database

Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 5.41)OA: hybridTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (32)

Ying K. Tam ORCID,Benjamin W. Lee ORCID,Jacob W. Myerson ORCID,D. Alan Herbst ORCID,Raisa Y. Kiseleva ORCID

Live enrichment

PubMed:40668829 PMC:PMC12304964 OpenAlex:https://openalex.org/W4412488480

NIH

Grant: RO1 HL155106

NHLBI NIH HHS

Grant: T32 HL007843

NHLBI NIH HHS

Grant: R01 HL155106

NHLBI NIH HHS

Grant: R01 HL169448

FWCI

5.41

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2409266122

publisherhttps://doi.org/10.1073/pnas.2409266122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2409266122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40668829

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12304964/

Fields of Study

RNA Interference and Gene DeliveryViral Infections and Immunology ResearchPARP inhibition in cancer therapyAnimalsSarcoplasmic Reticulum Calcium-Transporting ATPasesMyocardiumMiceMyocardial ContractionRatsRNA, Small InterferingNanoparticlesApolipoproteins EMice, KnockoutMyocytes, CardiacMaleLipids

MeSH Terms

AnimalsApolipoproteins ELipidsMaleMyocardial ContractionMyocardiumMice, KnockoutMyocytes, CardiacRNA, Small InterferingMiceRatsSarcoplasmic Reticulum Calcium-Transporting ATPasesNanoparticles

Keywords

ContractilityIn vivoApolipoprotein EEndoplasmic reticulumPharmacologyMedicineChemistryCell biologyInternal medicineBiologyDiseasemRNASiRNASerca2Lipid NanoparticlesCardiac Drug Delivery

Sustainable Development Goals

SDG 0: Good health and well-being