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Functional inversion of circadian regulator REV-ERBα leads to tumorigenic gene reprogramming

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2411321121Source: DataRank Database

Functional inversion of circadian regulator REV-ERBα leads to tumorigenic gene reprogramming is a research paper published in Proceedings of the National Academy of Sciences (2024). On theSindex it has a DataRank of 0.385. It has been cited 12 times.

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0.385DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 2.27)OA: hybridTopics (111)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.385

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (17)

Xiong Zhang ORCID,Demin Cai ORCID,Xingling Zheng,Xuan Zhao ORCID,June X. Zou ORCID

Live enrichment

PubMed:39383000 PMC:PMC11494309 OpenAlex:https://openalex.org/W4403243054

NCI NIH HHS

Grant: P30 CA014195

NCI NIH HHS

Grant: P01 CA265762

NCI NIH HHS

Grant: P30 CA093373

NCI NIH HHS

Grant: R35 CA242443

NCI NIH HHS

Grant: R01 CA250338

BLRD VA

Grant: I01 BX004271

NCI NIH HHS

Grant: R01 CA220468

NCI NIH HHS

Grant: R01 CA206222

NCI NIH HHS

Grant: R01 CA224900

NCI NIH HHS

Grant: R01 CA259081

National Institutes of Health

Grant: 3P30CA093373-07S2

Cancer Center Support Grant - P30

National Institutes of Health

Grant: 5R01CA220468-05

Organic nanoparticles for dual MRI-guided therapeutic selection and ovarian cancer drug delivery

National Institutes of Health

Grant: 5R01CA259081-03

Targeting aberrant circadian regulator in advanced prostate cancer

National Institutes of Health

Grant: 5R01CA224900-05

Therapeutic targeting of orphan NR in ER-negative breast cancer

FWCI

2.27

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1073/pnas.2411321121

publisherhttps://doi.org/10.1073/pnas.2411321121

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39383000

repositoryhttps://escholarship.org/uc/item/641071cv

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11494309

Fields of Study

Circadian rhythm and melatoninEpigenetics and DNA MethylationHormonal Regulation and Hypertension0302 clinical medicine03 medical and health sciencesNuclear Receptor Subfamily 1, Group D, Member 1HumansAnimalsCircadian RhythmCarcinogenesisMiceGene Expression Regulation, NeoplasticTranscription FactorsHepatocyte Nuclear Factor 3-alphaSignal TransductionCell Line, TumorNeoplasmsCell Cycle ProteinsNuclear Receptor Co-Repressor 1Bromodomain Containing Proteins

MeSH Terms

Bromodomain Containing ProteinsAnimalsCircadian RhythmHumansNeoplasmsTranscription FactorsSignal TransductionGene Expression Regulation, NeoplasticCell Cycle ProteinsCell Line, TumorMiceHepatocyte Nuclear Factor 3-alphaNuclear Receptor Subfamily 1, Group D, Member 1Nuclear Receptor Co-Repressor 1Carcinogenesis

Keywords

BiologyCorepressorRegulatorReprogrammingCell biologyChromatinTranscription factorFOXA1Nuclear receptorActivator (genetics)Cancer researchBromodomainGeneticsEpigeneticsGeneLiverProstateAntagonistCrpcRev-erbαCarcinogenesisCell Cycle ProteinsCell Cycle Proteins (mesh)MiceBromodomain Containing ProteinsGroup DNuclear Receptor Co-Repressor 1 (mesh)Neoplasms2.1 Biological and endogenous factorsAnimals (mesh)32 Biomedical and Clinical Sciences (for-2020)CancerCancer (rcdc)Humans (mesh)Neoplasms (mesh)TumorREV-ERB alphaMice (mesh)Transcription Factors (mesh)Biological SciencesCircadian RhythmGene Expression Regulation, NeoplasticTumor (mesh)Signal TransductionHepatocyte Nuclear Factor 3-alphaMember 1570Circadian Rhythm (mesh)Nuclear Receptor Subfamily 11.1 Normal biological development and functioning610Member 1 (mesh)Cell LineHepatocyte Nuclear Factor 3-alpha (mesh)Cell Line, TumorBromodomain Containing Proteins (mesh)HumansAnimalsNuclear Receptor Co-Repressor 11.1 Normal biological development and functioning (hrcs-rac)Neoplastic31 Biological Sciences (for-2020)Neoplastic (mesh)Biomedical and Clinical SciencesGenetics (rcdc)Human Genome2.1 Biological and endogenous factors (hrcs-rac)Cancer (hrcs-hc)Human Genome (rcdc)Carcinogenesis (mesh)3101 Biochemistry and Cell Biology (for-2020)Gene Expression RegulationNuclear Receptor Subfamily 1, Group D, Member 1Signal Transduction (mesh)Biochemistry and Cell BiologyTranscription Factors

Sustainable Development Goals

SDG 0: Good health and well-being