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Pharmacological inhibition of HIF2 protects against bone loss in an experimental model of estrogen deficiency

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2416004121Source: DataRank Database

Pharmacological inhibition of HIF2 protects against bone loss in an experimental model of estrogen deficiency is a research paper published in Proceedings of the National Academy of Sciences (2024). On theSindex it has a DataRank of 0.269. It has been cited 5 times.

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0.269DataRank · unranked

Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.91)OA: hybridTopics (72)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (11)

Elena Sabini ORCID,Katherine Beigel ORCID,Mohd Parvez Khan ORCID,X. Sherry Liu ORCID,Dian Wang ORCID

Live enrichment

PubMed:39602268 PMC:PMC11626196 OpenAlex:https://openalex.org/W4404754387

HHS | National Institutes of Health

Grant: R01 AR073022-01A1

NIAMS NIH HHS

Grant: P30 AR069619

NIAMS NIH HHS

Grant: P30 AR069620

NIAMS NIH HHS

Grant: R01 AR073022

National Institutes of Health

Grant: 5R01AR073022-05

HIF-2alpha, a Novel Regulator of Osteoblastogenesis

National Institutes of Health

Grant: 5P30AR069620-05

Michigan Integrative Musculoskeletal Health Core Center (Resource-based Center)

FWCI

0.91

Citation Percentile

0.7%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2416004121

publisherhttps://doi.org/10.1073/pnas.2416004121

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2416004121

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39602268

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11626196

Fields of Study

Cancer, Hypoxia, and MetabolismBone Metabolism and DiseasesBone health and treatments0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsEstrogensMiceFemaleBasic Helix-Loop-Helix ProteinsOsteoblastsOsteogenesisDisease Models, AnimalBone ResorptionOvariectomyOsteoporosisCancellous BoneMice, KnockoutTranscription FactorsEndothelial PAS Domain-Containing Protein 1

MeSH Terms

Cancellous BoneEndothelial PAS Domain-Containing Protein 1AnimalsBone ResorptionDisease Models, AnimalEstrogensFemaleOsteoblastsOsteogenesisOsteoporosisOvariectomyTranscription FactorsMice, KnockoutMiceBasic Helix-Loop-Helix ProteinsBasic Helix-Loop-Helix Transcription Factors

Keywords

OsteoblastEndocrinologyOsteoporosisBone resorptionInternal medicineBone marrowProgenitor cellEstrogenChemistryBone remodelingBone cellCell biologyBiologyMedicineStem cellIn vitroBiochemistryHypoxiaOsteoblastsHif2Pt2399Basic Helix-Loop-Helix ProteinsMice, KnockoutOvariectomyEstrogensBiological SciencesMiceDisease Models, AnimalOsteogenesisCancellous BonehIF2; hypoxia; osteoblasts; osteoporosis; PT2399AnimalsEndothelial PAS Domain-Containing Protein 1FemaleTranscription Factors

Sustainable Development Goals

SDG 0: Good health and well-being