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Genomic analyses identify 15 risk loci and reveal HDAC2 , SOX2-OT , and IGF2BP2 in a naturally occurring canine model of gastric cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2416723122Source: DataRank Database

Genomic analyses identify 15 risk loci and reveal HDAC2 , SOX2-OT , and IGF2BP2 in a naturally occurring canine model of gastric cancer is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Data from: Genomic analyses identify 15 susceptibility loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally-occurring canine model of gastric cancer · Dryad

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (1 grants)Impact (FWCI 1.56)OA: hybridTopics (35)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

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Context only (not used in score)

Findable (2/2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Authors (12)

Sanne Hugen ORCID,Jessica J. Hayward ORCID,Thomas R. Famula ORCID,Janelle M. Belanger ORCID,Elizabeth A. McNiel ORCID

Live enrichment

PubMed:40445765 PMC:PMC12146739 OpenAlex:https://openalex.org/W4410888437

HHS | NIH | National Human Genome Research Institute

Grant: Intramural Program

FWCI

1.56

Citation Percentile

0.8%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2416723122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2416723122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2416723122

journalhttps://doi.org/10.1073/pnas.2416723122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40445765

Fields of Study

Veterinary Oncology ResearchEpigenetics and DNA MethylationHedgehog Signaling Pathway StudiesMedicineBiology

MeSH Terms

AnimalsDisease Models, AnimalDog DiseasesDogsRisk FactorsStomach NeoplasmsRNA-Binding ProteinsGenetic Predisposition to DiseasePolymorphism, Single NucleotideGenome-Wide Association StudySOXB1 Transcription Factors

Keywords

BiologyCancerGeneticsGenome-wide association studyGenetic architectureHaplotypeDiseaseGeneGenotypeOncologySingle-nucleotide polymorphismInternal medicineMedicineQuantitative trait locusAdenocarcinomaDogPdzrn3Belgian ShepherdBayesian Gwas

Sustainable Development Goals

SDG 0: Good health and well-being

Data from: Genomic analyses identify 15 susceptibility loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally-occurring canine model of gastric cancer

10.5061/dryad.pg4f4qrzsDryad

Genomic analyses identify 15 risk loci and reveal HDAC2 , SOX2-OT , and IGF2BP2 in a naturally occurring canine model of gastric cancer

FAIR Checklist

Authors (12)

Funding (1 grants)

Impact

Open Access

Topics

Linked Datasets (1)

Annotations (Europe PMC)