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Fungal-derived methyldeoxaphomins target Plasmodium falciparum segregation through the inhibition of PfActin1

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2418871122Source: DataRank Database

Fungal-derived methyldeoxaphomins target Plasmodium falciparum segregation through the inhibition of PfActin1 is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (6 grants)Impact (FWCI 1.01)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Jin Woo Lee ORCID,Jennifer E. Collins ORCID,Samuel Schaefer ORCID,Daisy Chen ORCID,Flore Nardella ORCID

Live enrichment

PubMed:40138707 PMC:PMC11874377 OpenAlex:https://openalex.org/W4407695374

NIAID NIH HHS

Grant: R01 AI152533

HHS | NIH

Grant: R01 AI154777

Bill and Melinda Gates Foundation

Grant: INV-039628

NIAID NIH HHS

Grant: R01 AI090141

National Institutes of Health

Grant: 1S10OD026929-01

Illumina NovaSeq 6000 Sequencing System

National Institutes of Health

Grant: 5R01AI154777-03

Novel Antimalarials from Fungi

FWCI

1.01

Citation Percentile

0.7%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2418871122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2418871122

journalhttps://doi.org/10.1073/pnas.2418871122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40138707

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11874377

Fields of Study

Malaria Research and ControlPeptidase Inhibition and AnalysisMultiple Myeloma Research and Treatments01 natural sciences0104 chemical sciencesPlasmodium falciparumProtozoan ProteinsAntimalarialsMolecular Docking SimulationHypocrealesStructure-Activity RelationshipHumansAdenosine Triphosphatases

MeSH Terms

Adenosine TriphosphatasesAntimalarialsHumansHypocrealesPlasmodium falciparumStructure-Activity RelationshipProtozoan ProteinsMolecular Docking Simulation

Keywords

Plasmodium falciparumAllosteric regulationSchizogonyDocking (animal)BiologyIn vitroCell biologyBiochemistryEnzymeMalariaImmunologyFungi-Derived Natural ProductMethyldeoxaphominMolecular Docking SimulationAdenosine TriphosphatasesAntimalarialsStructure-Activity RelationshipHypocrealesProtozoan ProteinsHumansBiological Sciences

Sustainable Development Goals

SDG 0: Responsible consumption and production