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Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2421467122Source: DataRank Database

Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 1.62)OA: hybridTopics (60)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Jiangbo Wu ORCID,Thomas D. Pollard ORCID,Gregory A. Voth ORCID,Sahithya S. Iyer ORCID

Live enrichment

PubMed:40048273 PMC:PMC11912402 OpenAlex:https://openalex.org/W4408186281

HHS | NIH | National Institute of General Medical Sciences

Grant: R01GM063796

HHS | NIH | National Institute of General Medical Sciences

Grant: R01GM026132

HHS | NIH

Grant: 1S10OD028655-01

Beagle-3: A Shared GPU Cluster for Biomolecular Sciences

NIH HHS

Grant: S10 OD028655

FWCI

1.62

Citation Percentile

0.8%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2421467122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2421467122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2421467122

journalhttps://doi.org/10.1073/pnas.2421467122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40048273

Fields of Study

Cellular Mechanics and InteractionsCardiomyopathy and Myosin StudiesForce Microscopy Techniques and Applications0301 basic medicine03 medical and health sciencesActin-Related Protein 2-3 ComplexActinsMolecular Dynamics SimulationHumansProtein BindingWiskott-Aldrich Syndrome Protein, NeuronalBinding SitesAnimalsActin-Related Protein 3Actin CytoskeletonProtein Conformation

MeSH Terms

ActinsAnimalsBinding SitesHumansActin CytoskeletonProtein BindingProtein ConformationWiskott-Aldrich Syndrome Protein, NeuronalActin-Related Protein 2-3 ComplexActin-Related Protein 3Molecular Dynamics Simulation

Keywords

Protein filamentMonomerMetadynamicsActinBiophysicsNucleationActin remodelingActin-binding proteinMolecular dynamicsMaterials scienceCytoskeletonChemistryCell biologyActin cytoskeletonBiologyPolymerCellBiochemistryComputational chemistryArp2/3 ComplexNucleation-promoting FactorActin Filament BranchingBinding SitesProtein ConformationWiskott-Aldrich Syndrome Protein, NeuronalBiological SciencesMolecular Dynamics SimulationActin-Related Protein 2-3 ComplexActinsActin-Related Protein 3HumansAnimalsProtein Binding

Sustainable Development Goals

SDG 0: Affordable and clean energy

Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer

FAIR Checklist

Authors (4)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)