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BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2424367122Source: DataRank Database

BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)Impact (FWCI 2.17)OA: hybridTopics (69)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Soner Yildiz ORCID,E. Kaitlynn Allen ORCID,Hans Petersen ORCID,Mark E. Peeples ORCID,Sara S. El Zahed ORCID

Live enrichment

PubMed:40627391 PMC:PMC12280918 OpenAlex:https://openalex.org/W4412110855

HHS | National Institutes of Health

Grant: R01AI148180

HHS | National Institutes of Health

Grant: RO1HL068111 R01HL140839

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: 75N93021C00014

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: 75N93021C00016

HHS | National Institutes of Health

Grant: R01AI154470

NIAID NIH HHS

Grant: U01 AI187057

NHLBI NIH HHS

Grant: R01 HL140839

NHLBI NIH HHS

Grant: R01 HL171164

NCI NIH HHS

Grant: P30 CA016058

NHLBI NIH HHS

Grant: R01 HL068111

National Institutes of Health

Grant: 1R01HL140839-01

Wood Smoke and Chronic Mucous Hypersecretion

National Institutes of Health

Grant: 5R01AI148180-04

The role of Bik in the replication and severity of influenza A virus

National Institutes of Health

Grant: 5R01HL068111-08

REGULATION OF MUCOUS CELL METAPLASIA IN ASTHMA

National Institutes of Health

Grant: 3P30CA016058-15S1

CORE--HORMONE RECEPTOR LABORATORY

National Institutes of Health

Grant: 1U01AI187057-01

Influenza Modeling of Correlates of Protection for Optimal Immune Dynamics and Evolution.

National Institutes of Health

Grant: 5R01AI154470-03

Immunobiology of Influenza Virus-related Critical Illness in Young Hosts

FWCI

2.17

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2424367122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2424367122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2424367122

journalhttps://doi.org/10.1073/pnas.2424367122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40627391

Fields of Study

Influenza Virus Research StudiesImmune Cell Function and Interactioninterferon and immune responses0301 basic medicine03 medical and health sciencesAnimalsHumansProteasome Endopeptidase ComplexMiceInfluenza, HumanVirus ReplicationOrthomyxoviridae InfectionsApoptosis Regulatory ProteinsMembrane ProteinsInfluenza A virusRisk FactorsMice, Inbred C57BLViral Core ProteinsEpithelial CellsRNA-Binding ProteinsPolymorphism, Single NucleotideNucleocapsid Proteins

MeSH Terms

AnimalsEpithelial CellsHumansInfluenza, HumanMembrane ProteinsMice, Inbred C57BLOrthomyxoviridae InfectionsInfluenza A virusRisk FactorsViral Core ProteinsVirus ReplicationRNA-Binding ProteinsNucleocapsid ProteinsPolymorphism, Single NucleotideProteasome Endopeptidase ComplexApoptosis Regulatory ProteinsMice

Keywords

Viral replicationBiologyInfluenza A virusViral loadVirologyNucleoproteinImmunologyVirusHost factorProteasomeSNPBikBeta 5Proteasome Endopeptidase ComplexViral Core ProteinsMembrane ProteinsRNA-Binding ProteinsEpithelial CellsBiological SciencesNucleocapsid ProteinsVirus ReplicationPolymorphism, Single NucleotideMice, Inbred C57BLMiceOrthomyxoviridae InfectionsRisk FactorsInfluenza, HumanAnimalsHumansApoptosis Regulatory Proteins