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Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2501046122Source: DataRank Database

Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.72)OA: hybridTopics (50)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Kathryn E. Huey‐Tubman ORCID,Zhiyuan Mao ORCID,Magnus A. G. Hoffmann ORCID,Pamela J. Björkman ORCID,Richard M. Murray ORCID

Live enrichment

PubMed:41397133 PMC:PMC12745732 OpenAlex:https://openalex.org/W4417341014

Chan Zuckerberg Initiative

Grant: 2023-332386

DOD | USA | AFC | CCDC | ARO | Life Sciences Division, Army Research Office

Grant: W911NF-19-2-0026

NIAID NIH HHS

Grant: 75N93023D00005

NIDA NIH HHS

Grant: 75N95020D00005

ORFDO NIH HHS

Grant: 75N99020D00005

NHLBI NIH HHS

Grant: 75N92020D00005

NIAID NIH HHS

Grant: 75N93022D00005

FWCI

0.72

Citation Percentile

0.7%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2501046122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2501046122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2501046122

journalhttps://doi.org/10.1073/pnas.2501046122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41397133

Fields of Study

Immunotherapy and Immune ResponsesExtracellular vesicles in diseaseinterferon and immune responsesMedicineBiologyEndosomal Sorting Complexes Required for TransportHistocompatibility Antigens Class IExtracellular VesiclesT-LymphocytesLymphocyte ActivationInterferon-gammaAntigen PresentationTransfectionProtein BindingCell EngineeringImmunotherapyAntigen-Presenting CellsHEK293 CellsHumansLeukocytes, Mononuclear

MeSH Terms

Extracellular VesiclesAntigen-Presenting CellsHumansImmunotherapyInterferon-gammaLeukocytes, MononuclearLymphocyte ActivationPeptidesProtein BindingT-LymphocytesTransfectionHistocompatibility Antigens Class IAntigen PresentationEndosomal Sorting Complexes Required for TransportHEK293 CellsCell Engineering

Keywords

VesiclePeptideESCRTSecretionHEK 293 cellsImmune systemCytoplasmPeptide sequenceTransfectionExtracellular vesiclesautoimmune diseaseAntigen-presenting VesiclesCell-free ImmunoregulationPeptide Major Histocompatibility Complexes