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Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress–induced cytotoxicity

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2505359122Source: DataRank Database

Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress–induced cytotoxicity is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: hybridTopics (21)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Joo‐Youn Lee ORCID,Farbod A. Moghadam ORCID,Joseph Steiner ORCID,Soo-Kyung Kim ORCID,Neha Ganjur

Live enrichment

PubMed:41183202 PMC:PMC12625973 OpenAlex:https://openalex.org/W4415823577

HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: no numbef

HHS | NIH

Grant: R01HL155532 R35HL150807 and R35GM145239

National Research Council of Science and Technology

Grant: CAP23011-200

NIGMS NIH HHS

Grant: R35 GM145239

NHLBI NIH HHS

Grant: R35 HL150807

NHLBI NIH HHS

Grant: R01 HL155532

FWCI

0.00

Citation Percentile

0.2%

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1073/pnas.2505359122

publisherhttps://doi.org/10.1073/pnas.2505359122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2505359122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41183202

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12625973/

Fields of Study

Nerve injury and regenerationAlzheimer's disease research and treatmentsNuclear Receptors and Signaling

MeSH Terms

AnimalsHumansNeuronsOxidative StressNeuroprotective Agents

Keywords

PharmacophoreNeuroprotectionNeurodegenerationIn silicoCytotoxicityHEK 293 cellsOxidative phosphorylationTransfectionProgrammed cell deathVirtual ScreeningCarboxypeptidase ENeurotrophic Factor-α1Htr1e

Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress–induced cytotoxicity

FAIR Checklist

Authors (10)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)