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Ligand-specific regulation of a binary enhancer code dictating cellular senescence

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2506321122Source: DataRank Database

Ligand-specific regulation of a binary enhancer code dictating cellular senescence is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Enrichment:Funding (15 grants)OA: hybridTopics (25)IDs (PubMed, PMC)Annotations (2)

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Accessible (1/2)

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Reusable (0/3)

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Authors (8)

Meyer J. Friedman ORCID,Cagdas Tazearslan,Daria Merkurjev,Kenny Ohgi,Dario Meluzzi ORCID

Live enrichment

PubMed:40493192 PMC:PMC12184664

HHS | NIH | National Institute on Aging

Grant: AG061521

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK018477

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK039949

NIA NIH HHS

Grant: R01 AG061521

NIA NIH HHS

Grant: U19 AG056278

NIA NIH HHS

Grant: R01 AG057706

NIA NIH HHS

Grant: R01 AG069750

NIDDK NIH HHS

Grant: R01 DK039949

NIDDK NIH HHS

Grant: R01 DK018477

NIDDK NIH HHS

Grant: R01 DK127778

NIDDK NIH HHS

Grant: R37 DK039949

National Institutes of Health

Grant: 5R01AG069750-04

Regulatory Landscape of the Aging Human Ovary

National Institutes of Health

Grant: 1R01AG061521-01A1

Combinatorial regulation of the enhancer codes in senescence

National Institutes of Health

Grant: 5R01AG057706-05

Combinatorial Actions of Genetic Variants and Gender Bias of Alzherimer's Disease

National Institutes of Health

Grant: 1R01DK127778-01

Enhancer-based Immune and Beta Cell Dysregulation Underlying T1D Risk

hybridLicense: cc-by

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2506321122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2506321122

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12184664

Europe_PMChttps://europepmc.org/articles/PMC12184664

Europe_PMChttps://europepmc.org/articles/PMC12184664?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansActivinsLigandsSmad2 ProteinSmad3 ProteinTransforming Growth Factor beta2Enhancer Elements, GeneticCellular SenescenceSenescence-Associated Secretory Phenotype

Keywords

Cellular senescencep65EnhancersSmad2/3NfiTransforming Growth Factor beta2Enhancer Elements, GeneticHumansSmad2 ProteinSenescence-Associated Secretory PhenotypeSmad3 ProteinBiological SciencesLigandsActivins